Leah L. S.
- Country
- Spain
- Department
- Alergology
Research Overview
- Long-Term Safety and Efficacy Evaluation of Donidalorsen in Hereditary Angioedema Prophylaxis: An Open-Label Study
- Evaluation of Subcutaneous Immunotherapy with Der p 1/Der p 2/Der p 23 Allergens in Moderate/Severe Allergic Rhinitis/Rhinoconjunctivitis with/without Controlled Allergic Asthma
- Efficacy and Safety Evaluation of Navenibart in Hereditary Angioedema: A Phase 3 Randomized, Double-Blind, Placebo-Controlled Multicenter Trial
Data & Insights
Has run more than one trial at 31 of 56 partner sites.
Specializations
Allergic Rhinitis and Respiratory Allergy
Clinical research activity includes allergic rhinoconjunctivitis, allergic rhinitis, and house dust mite sensitization, with interest in symptom control and immunologic treatment approaches for upper-airway allergy.
- Allergic rhinoconjunctivitis
- House dust mite allergy
- Allergic asthma
Work in this area also extends to chronic allergic disease management in patients with overlapping respiratory symptoms.
Immune-Mediated and Inflammatory Disease
The investigator is involved in studies of atopic dermatitis, psoriasis, hidradenitis suppurativa, systemic lupus erythematosus, rheumatoid arthritis, and juvenile idiopathic arthritis, reflecting a broad therapeutic focus on immune dysregulation.
- Atopic dermatitis
- Systemic lupus erythematosus
- Juvenile idiopathic arthritis
Additional interest includes inflammatory bowel disease and other chronic autoimmune conditions requiring targeted immunomodulation.
Hematologic Malignancies
Research involvement covers acute myeloid leukemia, acute lymphoblastic leukemia, myelodysplastic syndromes, multiple myeloma, and lymphoma, with emphasis on advanced blood cancers and relapsed disease settings.
- Acute myeloid leukemia
- Multiple myeloma
- Diffuse large B-cell lymphoma
The portfolio also includes pediatric and adult hematologic oncology, supporting development of novel targeted and immune-based therapies.
Solid Tumors and Thoracic Oncology
Clinical trial activity includes non-small cell lung cancer, small cell lung cancer, breast cancer, ovarian cancer, renal cell carcinoma, and colorectal cancer, with a strong concentration in metastatic and biomarker-defined disease.
- Non-small cell lung cancer
- Breast cancer
- Renal cell carcinoma
Interest also extends to head and neck cancer, melanoma, pancreatic cancer, and other advanced solid tumors.
Neurology, Rare Disease, and Transplant-Related Care
Research participation includes multiple sclerosis, amyotrophic lateral sclerosis, epilepsy, migraine, Alzheimer’s disease, and myasthenia gravis, alongside rare neuromuscular and neurodegenerative disorders.
- Multiple sclerosis
- Amyotrophic lateral sclerosis
- Epilepsy
Additional therapeutic interests include lung transplant and liver disease contexts, as well as selected pediatric and hereditary conditions.
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