Laurent C.
- Country
- France
- Department
- Hépatologie
Research Overview
- N1T-MC-MALO: A Master Protocol for a Randomized, Controlled, Clinical Trial of Multiple Pharmacologic Agents in Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease Who Are at Increased Risk of Developing Major Adverse Liver Outcomes (SYNERGY-Outcomes); N1T-MC-TZ01 Tirzepatide in participants with high-risk MASLD; N1T-MC-RT01 Retatrutide in participants with high-risk MASLD
- Phase 3 Randomized Double‑Blind Placebo‑Controlled Study of Efimosfermin Alfa in Adults with Biopsy‑Confirmed F2–F3 Metabolic Dysfunction‑Associated Steatohepatitis
- Phase 3 Randomized Double‑Blind Placebo‑Controlled Study of Efimosfermin Alfa Safety and Tolerability in Adults with F2‑F3 Metabolic Dysfunction‑Associated Steatohepatitis
Data & Insights
Has run more than one trial at 170 of 279 partner sites.
Specializations
Liver Disease Expertise
This investigator specializes in treating advanced non-alcoholic steatohepatitis (NASH) and its progression to liver fibrosis. Their research encompasses both non-cirrhotic and cirrhotic stages of the disease.
- NASH Resolution Strategies
- Fibrosis Management
- Cirrhosis Treatment
Their work includes evaluation of liver histology improvements and fibrosis regression in patients.
Metabolic Health Focus
The investigator studies metabolic dysfunction-associated steatohepatitis (MASH) and its relationship with liver health. Their expertise extends to analyzing liver fat content and metabolic markers.
- Metabolic Liver Disease
- Hepatic Fat Reduction
- Metabolic Biomarkers
They evaluate therapeutic approaches for metabolic liver conditions and their clinical outcomes.
Clinical Outcomes Research
Their research focuses on liver-related clinical outcomes and mortality assessment in patients with chronic liver diseases. They monitor hepatic decompensation events and disease progression markers.
- Mortality Assessment
- Disease Progression Monitoring
- Long-term Patient Outcomes
The investigator tracks comprehensive clinical endpoints including liver transplantation needs and complications.
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