Laszlo N.
- Country
- Hungary
- Department
- NA
Research Overview
- Phase III Randomized Open‑Label Trial of Subcutaneous NXT007 Prophylaxis versus Intravenous Factor VIII Prophylaxis in Patients with Hemophilia A without Inhibitors
- Evaluation of Emicizumab Prophylaxis on Joint Health and Physical Activity in Patients Aged ≥13 to <70 with Severe or Moderate Hemophilia A Without FVIII Inhibitors
- Long-term Safety and Efficacy Evaluation of Fitusiran in Hemophilia A or B Patients With or Without Factor VIII or IX Inhibitory Antibodies
Data & Insights
Has run more than one trial at 17 of 77 partner sites.
Specializations
Cardiovascular Disease and Heart Failure
Clinical research activity includes a strong focus on atherosclerotic cardiovascular disease, acute myocardial infarction, acute coronary syndrome, stroke prevention, atrial fibrillation, and multiple forms of heart failure, including HFpEF, HFrEF, and HFmrEF.
- ASCVD and elevated lipoprotein(a)
- Chronic heart failure and worsening heart failure
- Refractory angina and hypertrophic cardiomyopathy
- Cardiometabolic risk and obesity
Therapeutic interests extend to lipid-lowering, antithrombotic, and heart-failure-directed interventions, with attention to long-term cardiovascular risk reduction.
Breast Cancer and Solid Tumors
Research involvement covers hormone receptor-positive breast cancer, HER2-negative and HER2-low disease, HER2-positive metastatic breast cancer, and broader settings of advanced solid tumors and metastatic malignancies.
- Locally advanced and metastatic breast cancer
- HER2-targeted therapy
- Endocrine-resistant disease
- Advanced solid tumor oncology
The therapeutic landscape includes contemporary oncology strategies for breast and other advanced cancers, with emphasis on precision-directed treatment options.
Gastroenterology and Inflammatory Bowel Disease
Clinical interests include Crohn’s disease, ulcerative colitis, fistulizing perianal Crohn’s disease, and short bowel syndrome, reflecting activity across inflammatory and absorptive gastrointestinal disorders.
- Crohn’s disease and ulcerative colitis
- Short bowel syndrome
- Gastroesophageal reflux disease-related erosive esophagitis
- Primary biliary cholangitis
Therapeutic work in this area spans immune-mediated intestinal disease and chronic digestive disorders requiring targeted medical management.
Hemostasis and Bleeding Disorders
Affiliation with I. Haemostasis Szakrendeles aligns with research in hemophilia A, hemophilia B, and related bleeding disorders, including patients with and without inhibitors.
- Hemophilia A and hemophilia B
- Prophylaxis and bleeding prevention
- Coagulation disorder management
- Joint health in hemophilia
Therapeutic interest also includes long-term control of bleeding risk and preservation of functional outcomes in inherited coagulation disorders.
Metabolic, Renal, and Ophthalmic Disorders
Additional research spans type 2 diabetes, obesity, chronic kidney disease, acute kidney injury, and eye diseases such as diabetic macular edema, wet age-related macular degeneration, and geographic atrophy.
- Type 2 diabetes and obesity
- Chronic kidney disease
- Diabetic macular edema
- Age-related macular degeneration
These areas reflect involvement in therapies addressing metabolic control, organ protection, and vision-threatening retinal disease.
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