László K.
- Country
- Hungary
- Department
- Központi Diagnosztikai Centrum (Radiológia)
Research Overview
- (21181) A multicenter, randomized, prospective double-blind, cross over Phase 3 study to evaluate the efficacy and safety of 0.04 mmol Gd/kg body weight of gadoquatrane for MRI in adults with known or suspected pathology of the central nervous system (CNS), compared to 0.1 mmol Gd/kg approved macrocyclic gadolinium-based contrast agents (GBCAs)
- (21197) A multicenter, randomized, prospective double-blind, cross over Phase 3 study to evaluate the efficacy and safety of 0.04 mmol Gd/kg body weight of gadoquatrane for MRI in adults with known or suspected pathology of any body region (except CNS), compared to 0.1 mmol Gd/kg approved macrocyclic gadolinium-based contrast agents (GBCAs)
Data & Insights
Has run more than one trial at 20 of 52 partner sites.
Specializations
Oncology
The investigator is involved in clinical research across a broad range of solid and hematologic malignancies, with particular interest in breast cancer, prostate cancer, renal cell carcinoma, gastric cancer, and bladder cancer.
- Advanced breast cancer
- Triple-negative breast cancer
- Metastatic castration-resistant prostate cancer
- Metastatic renal cell carcinoma
- Locally advanced or metastatic solid tumors
Research activity also includes lymphoblastic lymphoma, acute lymphoblastic leukemia, and malignancies defined by molecular features such as FGFR2b overexpression and ESR1 mutation.
Cardiovascular and cerebrovascular medicine
Clinical trial involvement covers major cardiovascular disease domains, including heart failure, acute heart failure, acute coronary syndrome, and prevention of recurrent vascular events.
- Acute ischemic stroke
- Atrial fibrillation
- Heart failure with preserved ejection fraction
- Refractory angina
- Peripheral thrombosis
The investigator also works in therapeutic areas linked to lipid lowering, thromboembolic prevention, and post-event cardiovascular risk reduction.
Immune-mediated and inflammatory disease
The investigator contributes to studies in chronic immune-mediated inflammatory diseases, with emphasis on inflammatory bowel disease, atopic dermatitis, psoriasis, and psoriatic arthritis.
- Crohn's disease
- Ulcerative colitis
- Moderate to severe atopic dermatitis
- Chronic plaque psoriasis
- Non-radiographic axial spondyloarthritis
Additional interest extends to juvenile psoriatic arthritis and other inflammatory conditions affecting the skin, gut, and musculoskeletal system.
Neurology and neuropsychiatry
Research involvement includes neurological and neuropsychiatric conditions such as stroke-related disability, psychosis associated with Alzheimer’s disease, and treatment of neurologic complications after vascular injury.
- Upper limb spasticity after stroke
- Psychosis associated with Alzheimer’s disease
- Transient ischemic attack
- Alzheimer’s disease-related psychosis
The therapeutic scope also includes imaging support for central nervous system pathology and related diagnostic evaluation.
Metabolic, musculoskeletal, and imaging-related care
The investigator is also active in trials addressing type 2 diabetes mellitus, obesity-related cardiovascular risk, knee osteoarthritis, and advanced magnetic resonance imaging contrast applications.
- Type 2 diabetes mellitus
- Knee osteoarthritis
- Contrast-enhanced MRI
- Respiratory syncytial virus prevention
- Neovascular age-related macular degeneration
This includes interest in conditions spanning musculoskeletal pain, pediatric prevention, and diagnostic radiology.
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