Lars Peter S.
- Country
- Denmark
- Department
- Endokrinologisk afd.
Research Overview
Data & Insights
Has run more than one trial at 0 of 18 partner sites.
Specializations
Colorectal Cancer
The investigator concentrates on colorectal cancer at stage II‑III, emphasizing tumors with somatic alterations in the PI3K signaling pathway.
- PIK3CA and PIK3R1 mutations
- PTEN loss
- Adjuvant therapeutic strategies
- Recurrence risk assessment
Research integrates molecular profiling to guide targeted interventions.
Immunotherapy in Oncology
Work includes evaluation of checkpoint inhibition, particularly with pembrolizumab, for achieving complete clinical responses.
- Neoadjuvant immunotherapy
- Clinical complete response rates
- Biomarker-driven patient selection
Efforts aim to define optimal treatment duration and combination approaches.
Type 1 Diabetes
Focuses on preservation of pancreatic β‑cell function in early type 1 diabetes and the impact of preventive strategies.
- β‑cell preservation
- Vaccination effects
- Risk stratification for cardiovascular disease
Research explores metabolic monitoring and intensified care models.
Cardiovascular Risk in Diabetes
Investigates the interplay between type 1 diabetes and cardiovascular outcomes, including heart failure and mortality.
- Intensified care pathways
- Novel mineralocorticoid receptor antagonists
- Cardiovascular event reduction
Studies aim to refine therapeutic targets for high‑risk diabetic populations.
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