Laetitia C.
- Country
- France
- Department
- Médecine interne
Research Overview
Data & Insights
Has run more than one trial at 0 of 33 partner sites.
Specializations
Pulmonary Infections & Mycobacterial Disease
The investigator concentrates on nontuberculous mycobacterial lung infection caused by Mycobacterium avium complex and related respiratory pathogens.
- Mycobacterium avium complex pulmonary disease
- Bronchiectasis with chronic Pseudomonas colonisation
- Acute respiratory distress syndrome secondary to infection
- Hospital‑acquired pneumonia in intensive care
- Invasive fungal lung infections
Research is conducted across three Parisian university hospitals, integrating internal medicine expertise with infectious disease management.
Oncology & Solid Tumor Therapeutics
Her work addresses advanced solid malignancies, focusing on therapeutic strategies for unresectable and metastatic disease.
- Advanced biliary tract carcinoma
- HER2‑positive gastric and gastro‑oesophageal junction cancers
- Unresectable non‑small cell lung cancer with KRAS G12C mutation
- High‑grade serous ovarian carcinoma
- Metastatic colorectal cancer with microsatellite instability
Collaborative trials at Assistance Publique‑Hôpitaux de Paris and affiliated sites support translational oncology initiatives.
Autoimmune & Systemic Rheumatic Diseases
She investigates immune‑mediated disorders, emphasizing disease‑modifying approaches for chronic inflammation.
- ANCA‑associated vasculitis
- Systemic lupus erythematosus with active nephritis
- Primary Sjögren’s syndrome
- Axial spondyloarthritis
- Psoriatic arthritis
Clinical protocols integrate internal medicine and rheumatology expertise within the three participating hospitals.
Cardiovascular & Metabolic Disorders
Her portfolio includes studies on cardiovascular risk reduction and metabolic disease management in adult populations.
- Acute coronary syndrome and myocardial infarction
- Heart failure with preserved ejection fraction
- Atherosclerotic cardiovascular disease in chronic kidney disease
- Type 2 diabetes mellitus after bariatric surgery
- Severe hypertension resistant to triple therapy
Investigations are coordinated through multidisciplinary cardio‑metabolic units at the affiliated sites.
Rare Genetic & Amyloidosis Conditions
She focuses on hereditary protein‑misfolding disorders, particularly those affecting the heart and peripheral nerves.
- Hereditary transthyretin amyloidosis with polyneuropathy
- Transthyretin amyloid cardiomyopathy
- APOL1‑mediated kidney disease
- Familial Mediterranean fever
- Primary hyperoxaluria
These rare‑disease studies leverage the specialized genetics and nephrology services of the three Parisian hospitals.
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