Leontine S.
- Country
- The Netherlands
- Department
- Oncology
Research Overview
- Evaluation of Trastuzumab Deruxtecan in Unresectable/Metastatic HER2-low or HER2 IHC0 Breast Cancer: A Multicenter, Open-label Study
- Evaluation of Hypersensitivity Reactions in Solid Tumor Patients Undergoing Paclitaxel Chemotherapy with and without Dexamethasone Premedication
- Evaluation of CDK4/6 Inhibitors Abemaciclib, Palbociclib, and Ribociclib in HR+/HER2- Metastatic Breast Cancer: A Randomized Clinical Trial
Data & Insights
Has run more than one trial at 10 of 107 partner sites.
Specializations
Breast Cancer Research
Specializes in advanced therapeutic approaches for hormone receptor-positive and HER2-low breast cancer. Investigates innovative treatment strategies involving CDK4/6 inhibitors and targeted therapies like trastuzumab deruxtecan.
- Metastatic breast cancer management
- Hormone receptor therapy optimization
- Novel targeted therapeutic approaches
Focuses on developing treatment sequences for advanced breast cancer stages.
Gastrointestinal Oncology
Concentrates on treatment strategies for metastatic pancreatic cancer and colorectal cancer. Explores timing optimization of systemic treatments and personalized dosing approaches, particularly in elderly patients.
- Pancreatic cancer treatment timing
- Colorectal cancer chemotherapy optimization
- Geriatric oncology adaptations
Specializes in quality-of-life oriented treatment approaches for advanced gastrointestinal cancers.
Supportive Care Innovation
Investigates optimization of chemotherapy premedication protocols, particularly in solid tumor treatments. Studies the management of hypersensitivity reactions and treatment tolerability enhancement.
- Premedication protocol development
- Chemotherapy-related adverse events
- Treatment safety optimization
Focuses on improving patient comfort and safety during chemotherapy administration.
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