Krisztina K.
- Country
- Hungary
- Department
- Private praxis
Research Overview
- Inclisiran for Prevention of Major Adverse Cardiovascular Events in High-Risk Primary Prevention Patients with Atherosclerotic Cardiovascular Disease
- Evaluation of Tovinontrine on NT-proBNP Levels in Adults with Chronic Heart Failure with Preserved Ejection Fraction: A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study
- Phase 2 Randomized Double-Blind Placebo-Controlled Study of Tovinontrine in Adults with Heart Failure with Reduced Ejection Fraction
Data & Insights
Has run more than one trial at 756 of 1359 partner sites.
Specializations
Cardiovascular risk reduction
Clinical research activity is centered on prevention of major cardiovascular events in people with atherosclerotic cardiovascular disease, high cardiovascular risk, and related metabolic risk profiles. The work includes therapies targeting lipid-driven risk, vascular inflammation, and event prevention in established or primary-prevention settings.
- Major adverse cardiovascular events (MACE)
- Lipids and lipoprotein(a)
- Hypertension and obesity
- Type 2 diabetes with cardiovascular disease
This area reflects involvement in therapies aimed at reducing myocardial infarction, stroke, and coronary revascularization risk.
Heart failure and post-infarction care
Another major focus is heart failure, including heart failure with preserved ejection fraction, heart failure with reduced ejection fraction, and broader left ventricular dysfunction after myocardial infarction. The trial portfolio also includes symptomatic and event-based approaches in chronic and acute heart failure populations.
- HFpEF and HFrEF
- Post-myocardial infarction ventricular impairment
- Worsening heart failure
- Cardiorenal-metabolic overlap
Therapeutic interest extends to strategies that address clinical outcomes, functional status, and biomarker-guided heart failure management.
Pulmonary and airway disease
Clinical involvement also covers chronic respiratory disorders, with emphasis on chronic obstructive pulmonary disease, asthma, and bronchiectasis. Research activity includes treatment options for airflow limitation, exacerbation prevention, and control of persistent respiratory symptoms.
- COPD
- Asthma
- Bronchiectasis
- Exacerbation prevention
This domain highlights interest in therapies designed to improve lung function and reduce respiratory events across obstructive airway disease.
Metabolic and anti-inflammatory disorders
The investigator’s research landscape includes obesity, overweight, and inflammatory diseases such as ulcerative colitis. Additional activity spans diabetic sensorimotor polyneuropathy, reflecting attention to metabolic complications and symptom burden in chronic disease.
- Obesity-related cardiovascular risk
- Ulcerative colitis
- Diabetic polyneuropathy
- Metabolic syndrome-related complications
These interests connect metabolic disease management with organ-specific outcomes and symptom control.
Neurological, vascular, and women’s health
Additional clinical interests include acute ischemic stroke, atrial fibrillation, and chronic venous ulcers, along with a women’s health study area involving primary dysmenorrhea and contraception. This broadens the portfolio into cerebrovascular care, thromboembolic prevention, wound healing, and reproductive health.
- Acute ischemic stroke
- Atrial fibrillation
- Chronic venous ulcers
- Primary dysmenorrhea and contraceptive efficacy
These areas show involvement in both vascular event prevention and targeted care for gynecologic and wound-related conditions.
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