Kristoffer R.
- Country
- Denmark
- Department
- Department of Oncology
Research Overview
- Phase 1 Study of SHP2 Inhibitor BBP-398 and KRAS-G12C Inhibitor Sotorasib in Advanced Solid Tumors with KRAS-G12C Mutation
- Safety, Pharmacokinetics, and Efficacy of RO7567132 Alone and with Atezolizumab in Patients with Advanced or Metastatic Solid Tumors
- Evaluation of Safety, Tolerability, Pharmacokinetics, and Preliminary Anti-Tumor Activity of Inavolisib with Paclitaxel in Locally Advanced or Metastatic Solid Tumors
Data & Insights
Has run more than one trial at 51 of 124 partner sites.
Specializations
Hematologic Oncology
Investigator leads trials in blood‑cancer therapeutics, targeting malignant proliferation of hematopoietic cells.
- Acute myeloid leukemia
- Chronic lymphocytic leukemia
- B‑cell non‑Hodgkin lymphoma
- Multiple myeloma
- Acute lymphoblastic leukemia
Ten interventional studies across five Danish university hospitals.
Solid Tumor Oncology
Clinical programs address major solid‑tumor entities with molecularly driven strategies.
- Non‑small cell lung cancer
- Breast cancer
- Colorectal cancer
- Prostate cancer
- Ovarian cancer
Trials evaluate targeted agents, immunotherapies and combination regimens.
Cardiovascular Medicine
Research includes acute coronary syndromes and chronic heart disease with a focus on vascular protection.
- Acute myocardial infarction
- Heart failure
- Atherosclerotic cardiovascular disease
- Stroke prevention
- Peripheral artery disease
Collaborations with cardiology units at Rigshospitalet support multicenter enrollment.
Neurology & Neurodegeneration
Investigations target neuro‑degenerative disorders and cerebrovascular injury.
- Alzheimer’s disease
- Amyotrophic lateral sclerosis
- Multiple sclerosis
- Ischemic stroke
- Brain tumor survivorship
Neuro‑oncology trials integrate imaging biomarkers for disease monitoring.
Rare Genetic & Metabolic Disorders
Trials explore therapeutic options for inherited syndromes affecting growth and metabolism.
- Klinefelter syndrome
- Achondroplasia
- Mitochondrial disease
- Cystic fibrosis
- Fabry disease
Patient‑centric protocols involve pediatric and adult cohorts.
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