Márk Kristóf F.
- Country
- Hungary
- Department
- Gyermekgyogyaszati Klinika, Tuzolto utcai reszleg, Neurologiai Osztaly
Research Overview
- A Randomized, Double-blind, Placebo-controlled Trial to Evaluate the Efficacy and Safety of Clemizole Hydrochloride as Adjunctive Therapy in Patients with Lennox-Gastaut Syndrome
- Evaluation of Cenobamate as Adjunctive Therapy in Patients Aged 12 and Older with Primary Generalized Tonic-Clonic Seizures: A Randomized, Double-Blind, Placebo-Controlled Study
- Efficacy and Safety of Carisbamate (YKP509) as Adjunctive Therapy for Lennox-Gastaut Syndrome-Associated Seizures in Pediatric and Adult Patients
Data & Insights
Has run more than one trial at 63 of 198 partner sites.
Specializations
Pediatric Gastroenterology and Inflammatory Bowel Disease
Clinical research activity includes ulcerative colitis, Crohn’s disease, and related inflammatory bowel disease indications in children and adolescents, with interest in therapies aimed at controlling intestinal inflammation and maintaining disease remission.
- Ulcerative colitis
- Crohn’s disease
- Inflammatory bowel disease
Therapeutic involvement also extends to short bowel syndrome and other digestive system disorders requiring advanced medical management.
Pediatric Immunology and Autoimmune Disease
The investigator is involved in clinical trials across autoimmune diseases and immune-mediated disorders, including juvenile idiopathic arthritis, systemic juvenile idiopathic arthritis, psoriatic arthritis, and systemic lupus erythematosus.
- Juvenile idiopathic arthritis
- Systemic lupus erythematosus
- Autoimmune diseases
Additional interests include myasthenia gravis, immune thrombocytopenia, hereditary angioedema, and other immune dysregulation conditions.
Pediatric Neurology and Seizure Disorders
Research involvement covers epilepsy and multiple seizure syndromes, with attention to focal-onset seizures, primary generalized tonic-clonic seizures, Lennox-Gastaut syndrome, and other refractory epileptic conditions.
- Epilepsy
- Focal-onset seizures
- Lennox-Gastaut syndrome
Clinical interest also includes spinal muscular atrophy, Dravet syndrome, and broader pediatric neurologic disease management.
Pediatric Oncology and Hematologic Malignancies
The clinical portfolio includes studies in acute lymphoblastic leukemia, acute myeloid leukemia, diffuse large B-cell lymphoma, multiple myeloma, and solid tumors such as neuroblastoma and Ewing sarcoma.
- Acute lymphoblastic leukemia
- Acute myeloid leukemia
- Diffuse large B-cell lymphoma
Additional trial activity includes pediatric brain tumors, rhabdomyosarcoma, and other advanced malignancies.
Pediatric Renal, Hepatobiliary, and Cardiovascular Conditions
The investigator also participates in trials addressing chronic kidney disease, proteinuria, kidney transplant rejection, and biliary atresia, reflecting a strong interest in pediatric organ-specific disease.
- Chronic kidney disease
- Biliary atresia
- Heart failure
Cardiovascular involvement includes heart failure, atherosclerotic cardiovascular disease, myocardial infarction, and related thrombotic and metabolic risk conditions.
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