Konstantinos T.
- Country
- Greece
- Department
- A Propedautic Pathology Clinic
Research Overview
- Effect of Orforglipron on Major Adverse Cardiovascular Events in Patients With Atherosclerotic Cardiovascular Disease and/or Chronic Kidney Disease
- Effect of Olpasiran on Major Cardiovascular Events in Patients with Atherosclerotic Cardiovascular Disease and Elevated Lipoprotein(a): A Randomized, Placebo-Controlled Study
- A Randomized, Placebo‑Controlled Trial of Zenagamtide (NNC0487‑0111) in Obese Patients with HFpEF or HFmrEF to Reduce CV Death and HF Hospitalization
Data & Insights
Has run more than one trial at 714 of 1342 partner sites.
Specializations
Cardiovascular Medicine
Clinical research activity includes atherosclerotic cardiovascular disease, acute myocardial infarction, ischemic stroke, and atrial fibrillation, with additional focus on heart failure, hypertension, and dyslipidaemia. The portfolio also extends to elevated lipoprotein(a), obesity-related cardiovascular risk, and cardiovascular death prevention.
- Acute coronary syndrome
- Stroke prevention
- Heart failure
- Lipid disorders
Research interests also include cardiometabolic inflammation, chronic kidney disease in cardiovascular populations, and cardiovascular risk reduction in patients with complex comorbidity.
Metabolic and Endocrine Disorders
The investigator is involved in studies on type 2 diabetes mellitus, obesity, overweight, and non-alcoholic steatohepatitis, alongside broader work in metabolic syndrome-related disease. This area also includes interest in glycaemic control and diabetic retinopathy.
- Type 2 diabetes
- Obesity
- Non-alcoholic steatohepatitis
- Diabetic eye disease
Therapeutic activity in this domain reflects attention to cardiometabolic risk, weight-related complications, and long-term metabolic disease management.
Respiratory and Pulmonary Vascular Disease
Research involvement includes pulmonary arterial hypertension, pulmonary hypertension associated with interstitial lung disease, idiopathic pulmonary fibrosis, and chronic obstructive pulmonary disease. Additional interest is seen in severe asthma, bronchiectasis, and community-acquired pneumonia.
- Pulmonary arterial hypertension
- Pulmonary fibrosis
- COPD
- Severe asthma
This therapeutic landscape also covers respiratory infection and post-viral inflammatory syndromes in hospital-based internal medicine settings.
Neurology, Neuroimmunology, and Mental Health
The investigator’s clinical trial activity spans multiple sclerosis, myasthenia gravis, chronic inflammatory demyelinating polyneuropathy, multifocal motor neuropathy, and acute ischemic stroke. The portfolio also includes Alzheimer’s disease, epilepsy, schizophrenia, and other cognitive disorders.
- Multiple sclerosis
- Autoimmune neuromuscular disease
- Neurodegenerative disease
- Psychiatric disease
Key therapeutic interests include immune-mediated neurological disease, relapse prevention, and functional recovery after neurological injury.
Oncology, Hematology, and Immune-Mediated Disease
Clinical research covers a broad range of solid tumors and hematologic malignancies, including non-small cell lung cancer, breast cancer, urothelial carcinoma, colorectal cancer, lymphoma, and acute myeloid leukemia. The investigator is also involved in myelofibrosis, multiple myeloma, and amyloidosis, together with autoimmune disorders such as ulcerative colitis, glomerulonephritis, and myasthenia gravis.
- Thoracic oncology
- Breast and genitourinary cancers
- Hematologic malignancies
- Immune-mediated disease
Therapeutic interests also extend to targeted cancer treatment, immunotherapy, and inflammatory disease control.
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