Knut M.
- Country
- Germany
- Department
- Klinik für Endokrinologie, Stoffwechsel- und Ernährungsmedizin
Research Overview
- Evaluation of Dapagliflozin and Lifestyle Intervention on Complication Risk in Prediabetes with Early Chronic Kidney Disease: A Randomized, Placebo-Controlled Trial
- Evaluation of Controlled-Ileal-Release Nicotinic Acid for Remission Induction in Prediabetes: A Phase II Randomized, Double-Blind, Placebo-Controlled Trial
- A Phase 2 Randomized, Placebo-controlled, Double-blind, Dose-ranging Study to Evaluate the Efficacy, Safety, and Tolerability of AMG 133 in Adult Subjects With Overweight or Obesity, With or Without Type 2 Diabetes Mellitus.
Data & Insights
Has run more than one trial at 5 of 26 partner sites.
Specializations
Endocrine Oncology
The investigator specializes in the treatment of medullary thyroid cancer, particularly focusing on cases involving RET mutations. Their expertise extends to evaluating novel therapeutic approaches for patients with progressive and advanced thyroid conditions.
- RET-mutant thyroid cancer management
- Advanced endocrine tumor therapy
- Targeted kinase inhibition
Rare Tumors and Genetic Conditions
The investigator has extensive experience in treating neuroendocrine tumors and von Hippel-Lindau disease-associated conditions. Their work encompasses various rare tumors including pheochromocytoma, paraganglioma, and pancreatic neuroendocrine tumors.
- VHL disease-associated tumors
- Neuroendocrine tumor therapy
- HIF-2α related malignancies
Metabolic and Renal Medicine
The investigator focuses on the intersection of chronic kidney disease and metabolic disorders, with particular attention to prediabetes. Their work involves innovative approaches to preventing kidney damage in early-stage renal conditions.
- Early-stage CKD management
- Prediabetes complications
- Renal protection strategies
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