Klemens B.
- Country
- Germany
- Department
- Nephrology
Research Overview
- A 3-month, phase 2, single-blind, randomised, no-treatment controlled study assessing efficacy and safety of Renaparin® for improvement of kidney graft function in deceased-donor transplant recipients, with an additional 9-month follow-up.
- A non-inferiority, randomised and controlled trial to compare the safety, tolerability and preliminary efficacy between standard and Torque Teno virus-guided immunosuppression in stable adult kidney transplant recipients with low immunological risk in the first year after transplantation
- Evaluation of Tegoprubart Versus Tacrolimus in Prophylaxis of Renal Allograft Rejection in Kidney Transplant Recipients
Data & Insights
Has run more than one trial at 34 of 137 partner sites.
Specializations
Transplant Rejection Prevention
This investigator specializes in evaluating novel approaches for prophylaxis of kidney transplant rejection, particularly focusing on different immunosuppressive therapies including tacrolimus formulations and innovative compounds like tegoprubart.
- Bioavailability studies of immunosuppressants
- Novel anti-rejection medications
- Long-term graft survival strategies
Kidney Transplant Complications
The investigator conducts research on managing post-transplant complications, with particular attention to antibody-mediated rejection and BK Polyomavirus infections in transplant recipients. Their work includes developing personalized approaches to immunosuppression dosing.
- Late antibody-mediated rejection treatment
- Viral infection management
- Immunosuppression optimization
Renal Function Enhancement
Research focuses on improving outcomes in end-stage renal disease and transplant recipients, including studies of ischemia-reperfusion injury prevention and novel treatments for chronic kidney disease. The investigator evaluates innovative therapeutic approaches such as dapagliflozin for renal and cardiovascular outcomes.
- Graft function optimization
- Kidney preservation techniques
- Combined renal-cardiovascular outcomes
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