Klaus M.
- Country
- Germany
- Department
- Klinik und Poliklinik fuer Haematologie, Zelltherapie, Haemostaseologie und Infektiologie
Research Overview
- Phase 1 Open-Label Dose Escalation and Expansion Study of CLN-049 in Acute Myeloid Leukemia with Measurable Residual Disease
- An open-label, single-arm, pilot study of Venetoclax in combination with 5 days Azacitidine in treatment-naïve subjects with acute myelogenous leukemia who are ≥18 years of age and not eligible for standard induction therapy (VENAZA-5S PILOT TRIAL)
- Efficacy of Ziftomenib Combined with Standard of Care Therapy in Patients with Untreated NPM1-Mutated or KMT2A-Rearranged Acute Myeloid Leukemia
Data & Insights
Has run more than one trial at 94 of 248 partner sites.
Specializations
Hematologic Malignancies
This investigator specializes in treating acute myeloid leukemia (AML), with particular emphasis on developing innovative therapeutic approaches for various disease states and patient populations.
- Newly diagnosed AML treatment strategies
- Management of measurable residual disease (MRD)
- Treatment-resistant AML cases
The investigator has extensive experience in evaluating novel therapeutic combinations for AML patients who are not eligible for standard treatment protocols.
Combination Therapies
A key focus area involves investigating combination treatments incorporating venetoclax with other therapeutic agents, particularly in conjunction with azacitidine for hematologic conditions.
- Alternative dosing strategies
- Novel drug combinations
- Targeted therapeutic approaches
The research encompasses both standard and modified treatment regimens to optimize patient outcomes.
Myeloid Disorders
The investigator conducts research in various myeloid disorders, including higher-risk myelodysplastic syndrome (MDS), exploring new therapeutic options and treatment strategies.
- Novel therapeutic agents
- Treatment of high-risk disease
- Innovative clinical approaches
Their work includes evaluation of emerging treatments for patients with various myeloid malignancies.
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