Kirsi L.
- Country
- Finland
- Department
- Oulu University Hospital (OYS), Department of Oncology/ Hematology
Research Overview
- Phase II Evaluation of Azacitidine and Low-Dose Venetoclax in Acute Myeloid Leukemia with Multi-Omics and Ex Vivo Drug Screening Integration
- Evaluation of Revumenib Combined with Azacitidine and Venetoclax in Newly Diagnosed NPM1-Mutated or KMT2A-Rearranged AML Patients Ineligible for Intensive Chemotherapy
- HOVON 181 AML: Bleximenib or Placebo in Combination with Standard Induction and Consolidation Therapy followed by Maintenance for the Treatment of Patients with Newly Diagnosed KMT2A-rearranged or NPM1-mutant Acute Myeloid Leukemia Eligible for Intensive Chemotherapy: a double-blind phase 3 study
Data & Insights
Has run more than one trial at 91 of 178 partner sites.
Specializations
Hematologic malignancies
Clinical research in acute lymphoblastic leukemia, acute myeloid leukemia, and myelodysplastic syndrome spans both pediatric and adult care, with attention to relapsed and refractory disease, high-risk biology, and minimal residual disease assessment.
- Acute lymphoblastic leukemia
- Acute myeloid leukemia
- Diffuse large B-cell lymphoma
- Multiple myeloma
- Follicular lymphoma
There is also involvement in lymphoma subtypes such as mantle cell lymphoma, marginal zone lymphoma, and B-cell lymphoma, reflecting a strong focus on advanced blood cancers and novel immunotherapeutic strategies.
Solid tumors in adult oncology
The investigator is active in trials for breast cancer, prostate cancer, ovarian cancer, endometrial cancer, and renal cell carcinoma, with interest in recurrent, metastatic, and high-risk disease settings.
- Breast cancer
- Prostate cancer
- Ovarian cancer
- Endometrial cancer
- Renal cell carcinoma
Research activity also includes non-small cell lung cancer, small cell lung cancer, and colorectal cancer, highlighting a therapeutic emphasis on systemic treatment options for advanced malignancies.
Pediatric oncology and rare cancers
Work in childhood cancer includes medulloblastoma, ependymoma, atypical teratoid/rhabdoid tumor, Ewing sarcoma, and rhabdomyosarcoma, alongside leukemia and lymphoma in younger patients.
- Medulloblastoma
- Atypical teratoid/rhabdoid tumor
- Ewing sarcoma
- Rhabdomyosarcoma
- Pediatric leukemia
Additional involvement in infant acute lymphoblastic leukemia, pediatric acute myeloid leukemia, and anaplastic large cell lymphoma underscores a broad pediatric hematology-oncology profile centered on rare and high-risk conditions.
Cardiovascular and thrombotic disease
Clinical interests extend to atherosclerotic cardiovascular disease, atrial fibrillation, stroke prevention, coronary artery disease, and venous thromboembolism, with attention to patients at elevated vascular risk.
- Atrial fibrillation
- Atherosclerotic cardiovascular disease
- Stroke prevention
- Coronary artery disease
- Venous thromboembolism
Research also includes acute coronary syndrome, myocardial infarction, and chronic kidney disease stage 5 with anticoagulation-related questions, reflecting therapeutic interest in cardiovascular protection and complication reduction.
Inflammation, lung disease, and metabolic disorders
The investigator is involved in studies of idiopathic pulmonary fibrosis, progressive pulmonary fibrosis, chronic lung disease, and bronchiectasis, as well as inflammatory skin and immune-mediated disorders such as atopic dermatitis, prurigo nodularis, and hidradenitis suppurativa.
- Idiopathic pulmonary fibrosis
- Progressive pulmonary fibrosis
- Atopic dermatitis
- Prurigo nodularis
- Obesity and metabolic syndrome
Additional therapeutic interests include type 1 diabetes, obesity, and endometriosis, showing engagement across chronic metabolic, endocrine, and women’s health conditions.
Related Investigators
Researchers in similar fields or departments
Want to know more about this investigator?
We can share extended profile information and contact details.
Is something out of date?
Tell us what needs correcting and we'll update this profile.