Kévin G.
- Country
- France
- Department
- Anesthésie
Research Overview
Data & Insights
Has run more than one trial at 0 of 32 partner sites.
Specializations
Breast Oncology
Research concentrates on triple‑negative breast cancer and HR‑positive HER2‑negative early breast cancer, exploring neoadjuvant immunotherapy, adjuvant CDK4/6 inhibition, and surgical prophylaxis.
- Neoadjuvant pembrolizumab in triple‑negative breast cancer
- Adjuvant ribociclib combined with endocrine therapy in HR‑positive HER2‑negative early breast cancer
- Pathologic complete response as a surrogate endpoint
- Antibiotic prophylaxis during lumpectomy for breast cancer
Emphasis is placed on treatment de‑escalation and personalized adjuvant strategies.
Interventional Cardiology
Focus lies on antiplatelet management after percutaneous coronary intervention in patients aged 65 years or older.
- Short dual antiplatelet therapy followed by P2Y12 monotherapy
- Outcomes with drug‑eluting stents in acute and chronic coronary syndromes
- Net clinical benefit composite endpoint (death, MI, stroke, major bleeding)
Studies aim to balance efficacy and safety in the elderly cardiovascular population.
Anal Oncology
Investigator evaluates intensified induction chemotherapy before standard chemoradiotherapy for locally advanced disease.
- Modified DCF induction chemotherapy
- Standard chemoradiotherapy alone
- 2‑year disease‑related event‑free survival
Target population includes T3‑4 or N1a‑c anal squamous cell carcinoma patients.
Perioperative Infection Control
Studies investigate prophylactic antibiotic use to prevent surgical site infections in breast surgery.
- Cefazolin versus placebo administered before lumpectomy
- Incidence of surgical site infection within 30 days
- Double‑blind randomized non‑inferiority design
Outcome measures focus on infection rates after partial mastectomy procedures.
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