Katrine Toubro G.
- Country
- Denmark
- Department
- Department of Oncology
Research Overview
Data & Insights
Has run more than one trial at 0 of 87 partner sites.
Specializations
Advanced Solid Tumor Oncology
The investigator concentrates on therapeutic strategies for advanced solid tumors that have progressed after prior lines of therapy.
- Non‑small cell lung cancer (NSCLC)
- Pancreatic ductal adenocarcinoma
- Biliary tract adenocarcinoma
- Small cell lung carcinoma
- Mesothelioma
Clinical focus includes biomarker‑driven selection such as tumor mutational burden and mismatch repair status.
Gynecologic Cancer Therapeutics
Research activity targets malignancies of the female reproductive system, emphasizing precision‑based treatment.
- Endometrial carcinoma
- Cervical squamous cell carcinoma
- Vulvar squamous cell carcinoma
- High‑risk ovarian cancer
- Uterine sarcoma exclusion criteria
Efforts include integration of immunotherapy and hormone‑targeted agents.
Immuno‑oncology & Checkpoint Inhibition
The investigator is engaged in trials evaluating immune checkpoint blockade across tumor types.
- PD‑1/PD‑L1 inhibitors
- CTLA‑4 targeting agents
- Combination with chemotherapy
- Biomarker selection (PD‑L1, MSI‑H, dMMR)
- Neoadjuvant immunotherapy approaches
Outcomes of interest include major pathological response and disease‑free survival.
Cardiovascular & Metabolic Disease Management in Oncology Patients
Clinical work integrates management of comorbid cardiovascular conditions alongside cancer therapy.
- Atherosclerotic cardiovascular disease (ASCVD)
- Heart failure with reduced ejection fraction
- Chronic kidney disease
- Hypertension in cancer patients
- Anticoagulation strategies in atrial fibrillation
Research evaluates safety of concurrent oncologic and cardiometabolic treatments.
Rare Molecularly Defined Cancers
Focus is placed on tumors characterized by specific genetic alterations.
- ALK‑positive NSCLC
- BRAF‑V600 mutated melanoma
- KRAS G12C‑positive lung cancer
- FGFR‑altered bladder cancer
- MTAP‑deleted biliary and pancreatic cancers
Therapeutic exploration includes targeted inhibitors and matched immunotherapy.
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