Sari J.
- Country
- Finland
- Department
- Comprehensive Cancer Center
Research Overview
- A Phase 3, Randomized, Double-Blind, Placebo-Controlled Clinical Trial of Pembrolizumab (MK-3475) as Monotherapy in the Adjuvant Treatment of Renal Cell Carcinoma Post Nephrectomy (KEYNOTE-564)
- Long-term Efficacy and Safety of Belzutifan and Lenvatinib in Patients with von Hippel-Lindau Disease-Associated Tumors and Other Advanced Solid Tumors
- Early Access Study of Zongertinib for the Treatment of Cancer in Patients Eligible for Anticancer Therapy
Data & Insights
Has run more than one trial at 151 of 358 partner sites.
Specializations
Hematologic Malignancies
Clinical research activity centers on acute myeloid leukemia, acute lymphoblastic leukemia, myelodysplastic syndrome, chronic myeloid leukemia, and a broad range of lymphoid neoplasms, including diffuse large B-cell lymphoma, follicular lymphoma, mantle cell lymphoma, chronic lymphocytic leukemia, and multiple myeloma.
- Relapsed/refractory leukemia
- B-cell non-Hodgkin lymphoma
- Plasma cell disorders
The portfolio also includes cellular therapy follow-up and treatment optimization in high-risk pediatric and adult blood cancers.
Solid Tumors and Precision Oncology
Investigations extend across prostate cancer, breast cancer, renal cell carcinoma, melanoma, colorectal cancer, endometrial cancer, pancreatic cancer, and non-small cell lung cancer, with attention to biomarker-defined disease.
- Advanced prostate cancer
- Renal and urothelial cancers
- Melanoma and gastrointestinal tumors
Research interests include targeted therapy, immunotherapy, and treatment strategies for metastatic solid tumors.
Neurovascular and Cardiovascular Disease
Clinical trial involvement includes acute ischemic stroke, transient ischemic attack, atrial fibrillation, coronary artery disease, heart failure, and peripheral arterial disease, along with vascular prevention in high-risk populations.
- Stroke prevention
- Thromboembolic risk reduction
- Cardiovascular disease
The therapeutic focus also covers anticoagulation strategies and acute neurovascular interventions.
Autoimmune, Inflammatory, and Renal Disorders
Research activity includes psoriatic arthritis, ulcerative colitis, systemic lupus erythematosus, primary sclerosing cholangitis, chronic kidney disease, and kidney transplantation–related conditions.
- Inflammatory bowel disease
- Autoimmune rheumatic disease
- Renal impairment and transplant medicine
Additional interests include proteinuria, transplant rejection, and immune-mediated organ complications.
Pediatric and Rare Diseases
The investigator is also involved in studies of pediatric leukemia, anaplastic large cell lymphoma, medulloblastoma, atypical teratoid/rhabdoid tumor, achondroplasia, and other rare genetic or developmental conditions.
- Pediatric oncology
- Rare genetic disorders
- Growth and developmental conditions
Work in this area also includes epileptic encephalopathies, hemophilia, and selected congenital disorders.
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