Katharina L.
- Country
- Austria
- Department
- Universitätsklinik für Gynäkologie und Geburtshilfe
Research Overview
- Sacituzumab Tirumotecan With or Without Bevacizumab Versus Standard of Care in Patients With Newly Diagnosed Advanced HRD-Negative Ovarian Cancer Following Platinum-Based Chemotherapy
- A Phase III, Randomized, Open-Label, Multicenter, Global Study of Puxitatug Samrotecan (AZD8205) Monotherapy versus Physician’s Choice of Chemotherapy in Participants with B7-H4-Selected Advanced/Metastatic Endometrial Cancer Who Progressed On or After Platinum-Based Chemotherapy and Anti-PD-1/Anti-PD-L1 Therapy (Bluestar-Endometrial01)
Data & Insights
Has run more than one trial at 34 of 150 partner sites.
Specializations
Gastroenterology and Inflammatory Bowel Disease
Clinical research activity includes therapeutic development for Crohn’s disease and ulcerative colitis, with attention to symptom control, mucosal healing, and long-term disease management.
- Crohn’s disease
- Ulcerative colitis
- Endoscopic response
Interest also extends to bowel urgency and broader treatment options for chronic immune-mediated gastrointestinal disease.
Breast Cancer and Gynecologic Oncology
Research involvement spans breast cancer, endometrial cancer, ovarian cancer, cervical cancer, and related gynecologic malignancies, with focus on advanced, recurrent, and high-risk disease settings.
- HER2-negative breast cancer
- Triple-negative breast cancer
- Endometrial cancer
- Ovarian cancer
- Cervical cancer
The portfolio reflects therapeutic interest in recurrence prevention, endocrine-resistant disease, and biomarker-defined oncology.
Respiratory Oncology and Thoracic Malignancies
Clinical trial activity includes non-small cell lung cancer, small cell lung cancer, and other thoracic tumors, covering both locally advanced and metastatic disease.
- Non-small cell lung cancer
- Small cell lung cancer
- Head and neck squamous cell carcinoma
- Esophageal cancer
Therapeutic interests also include targeted approaches for molecularly selected lung cancer and treatment strategies for advanced solid tumors.
Hematology, Lymphoma, and Myeloma
Research spans acute leukemia, chronic lymphocytic leukemia, lymphoma, multiple myeloma, and myelodysplastic syndromes, with involvement in both malignant and transplant-related hematologic care.
- Acute lymphoblastic leukemia
- Chronic lymphocytic leukemia
- Diffuse large B-cell lymphoma
- Multiple myeloma
- Myelodysplastic syndrome
Additional interest includes stem cell transplantation, graft-versus-host disease, and high-risk hematologic disease.
Autoimmune, Renal, and Cardiometabolic Disease
The investigator is also involved in trials addressing autoimmune disease, kidney disease, and cardiovascular disease, including conditions such as IgA nephropathy, ADPKD, ATTR cardiomyopathy, and atherosclerotic cardiovascular disease.
- IgA nephropathy
- Autosomal dominant polycystic kidney disease
- Transthyretin amyloid cardiomyopathy
- Atherosclerotic cardiovascular disease
Therapeutic focus also includes systemic lupus erythematosus, Sjögren’s syndrome, and other immune-mediated disorders.
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