Katharina K.
- Country
- Germany
- Department
- Paediatrische Haematologie, Onkologie und Stammzelltransplantation
Research Overview
Data & Insights
Has run more than one trial at 0 of 12 partner sites.
Specializations
Paediatric Acute Lymphoblastic Leukemia & Stem Cell Transplantation
Focused on curative approaches for Acute Lymphoblastic Leukemia in children, integrating risk‑adapted chemotherapy with allogeneic hematopoietic stem cell transplantation.
- Risk‑adapted induction regimens
- Targeted therapy for Ph+ disease
- Post‑transplant immune reconstitution
Goal is to increase event‑free survival while reducing long‑term sequelae.
Acute Myeloid Leukemia & Myelodysplastic Syndromes
Investigates therapeutic strategies for Acute Myeloid Leukemia and Myelodysplastic Syndrome, emphasizing molecular risk classification and transplantation conditioning.
- FLT3‑mutated disease management
- Measurable residual disease monitoring
- Reduced‑intensity conditioning protocols
Efforts target durable remission and improved transplant outcomes.
Lymphoid Malignancies – Lymphomas & Chronic Lymphocytic Leukemia
Addresses treatment of pediatric and adult Diffuse Large B‑Cell Lymphoma, Follicular Lymphoma, and Chronic Lymphocytic Leukemia through novel immunotherapeutic combinations.
- CD20‑directed monoclonal antibodies
- CAR‑T cell integration
- Maintenance strategies post‑remission
Seeks to enhance response depth and durability across lymphoma subtypes.
Graft‑Versus‑Host Disease & Transplant Immunology
Specializes in prevention and treatment of Chronic Graft‑Versus‑Host Disease and related immune complications following hematopoietic stem cell transplantation.
- JAK‑inhibitor based prophylaxis
- Biomarker‑guided immunosuppression
- Cellular therapies for refractory disease
Focus is on balancing graft‑versus‑leukemia effect with toxicity mitigation.
Rare Pediatric Solid Tumors – Neuroblastoma & Medulloblastoma
Explores targeted and cellular therapies for high‑risk Neuroblastoma and Medulloblastoma, incorporating molecular stratification and consolidation approaches.
- ALK‑directed agents
- High‑dose chemotherapy with autologous rescue
- Novel immunotherapy combinations
Aims to improve survival while preserving neurocognitive function.
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