Karine C.
- Country
- France
- Department
- Nutrition
Research Overview
- Evaluation of BP1.4979 in Female Patients with Moderate to Severe Binge Eating Disorder: A Double-Blind, Placebo-Controlled Pilot Study
- Phase 3 Randomized Double-Blind Placebo-Controlled Trial of Setmelanotide in Obesity with POMC/PCSK1, LEPR, NCOA1, or SH2B1 Gene Variants
- Evaluation of Allogeneic Fecal Microbiota Transfer on Glycemic Control in Post-Bariatric Surgery Patients with Non-Remission Type 2 Diabetes
Data & Insights
Has run more than one trial at 2 of 24 partner sites.
Specializations
Cardiometabolic Disease and Nutrition
The investigator is involved in clinical research focused on obesity, type 2 diabetes, metabolic dysfunction-associated steatohepatitis, and broader metabolic disorders, with attention to cardiovascular risk linked to excess weight and dysregulated metabolism.
- Obesity and overweight
- Type 2 diabetes
- MASH and NASH
- Atherosclerotic cardiovascular disease
Activity in this area also includes clinical interest in heart failure, hypertension, and cardiometabolic complications that intersect with liver and renal disease.
Hepatic and Digestive System Disorders
Her research landscape includes liver-focused studies in hepatocellular carcinoma, cirrhosis, portal hypertension, and hepatic encephalopathy, alongside chronic inflammatory conditions of the gastrointestinal tract.
- Hepatocellular carcinoma
- Cirrhosis and portal hypertension
- Inflammatory bowel disease
- Ulcerative colitis and Crohn's disease
The investigator is also associated with therapeutic questions in biliary tract cancer and other advanced digestive malignancies.
Autoimmune and Inflammatory Diseases
Her clinical trial involvement covers systemic immune-mediated diseases, including systemic lupus erythematosus, dermatomyositis, Sjögren’s syndrome, and systemic sclerosis, with additional interest in vasculitis and related organ involvement.
- Systemic lupus erythematosus
- Dermatomyositis and polymyositis
- Sjögren’s syndrome
- Systemic sclerosis
This therapeutic domain extends to uveitis, sarcoidosis, and other chronic inflammatory conditions requiring targeted immunomodulation.
Hematology and Oncology
The investigator participates in trials spanning acute myeloid leukemia, lymphoma, multiple myeloma, and solid tumors such as breast cancer, lung cancer, and ovarian cancer, reflecting a broad oncology portfolio.
- Acute myeloid leukemia
- Diffuse large B-cell lymphoma
- Multiple myeloma
- Advanced solid tumors
Her work also includes malignancies of the gastrointestinal tract, genitourinary system, and head and neck, with emphasis on treatment innovation in difficult-to-treat disease.
Cardiovascular, Renal, and Critical Care Medicine
Her trial activity includes acute coronary syndrome, myocardial infarction, heart failure, stroke, septic shock, and acute kidney injury, showing involvement in high-acuity medical care and organ-supportive therapy.
- Acute coronary syndrome
- Heart failure
- Acute kidney injury
- Sepsis and critical care
Additional interest is evident in cardiogenic shock, thromboembolic disease, and complex renal conditions including chronic kidney disease and transplant-related complications.
Related Investigators
Researchers in similar fields or departments
Want to know more about this investigator?
We can share extended profile information and contact details.
Is something out of date?
Tell us what needs correcting and we'll update this profile.