Karaszewski B.
- Country
- Poland
- Department
- Klinika Neurologii Dorosłych
Research Overview
- Evaluation of Mechanical Thrombectomy Plus Acetylsalicylic Acid Versus Acetylsalicylic Acid Alone in Acute Ischemic Stroke with Large Vessel Occlusion
- Phase II Randomized, Double-Blind, Placebo-Controlled Study of Intravenous Alteplase Post-Andexanet Alfa Reversal in Acute Ischemic Stroke on DOAC Therapy
Data & Insights
Has run more than one trial at 3 of 7 partner sites.
Specializations
Neuro-oncology and central nervous system malignancies
Clinical research includes glioblastoma, brain metastases, and other advanced brain tumor settings, with attention to difficult-to-treat intracranial disease and tumor control in neurologic oncology.
- Glioblastoma
- Brain metastases
- Unresectable central nervous system tumors
Work in this area aligns with therapeutic development for aggressive intracranial cancers and neurologically complex malignancies.
Thoracic oncology and lung cancer
The investigator is actively involved in studies of non-small cell lung cancer and small cell lung cancer, including molecularly defined and advanced disease, with interest in both localized and metastatic thoracic tumors.
- Non-small cell lung cancer
- Small cell lung cancer
- EGFR- and ALK-driven lung cancer
This research domain also extends to thoracic tumors with actionable alterations and treatment-resistant disease.
Hematologic malignancies and cellular therapy
Research activity covers a broad spectrum of blood cancers, including lymphoma, multiple myeloma, acute myeloid leukemia, and myelodysplastic syndromes, together with CAR T-cell therapy and other advanced immunotherapies.
- Diffuse large B-cell lymphoma
- Multiple myeloma
- Acute myeloid leukemia
Additional interest includes chronic lymphocytic leukemia, mantle cell lymphoma, and relapsed or refractory hematologic disease.
Breast cancer, gynecologic oncology, and other solid tumors
The investigator participates in trials across breast cancer, ovarian cancer, endometrial cancer, cervical cancer, and head and neck squamous cell carcinoma, with emphasis on advanced, recurrent, and biomarker-defined disease.
- Hormone receptor-positive breast cancer
- Triple-negative breast cancer
- Ovarian cancer
Related activity includes melanoma, gastrointestinal cancers, and other advanced solid tumors requiring novel systemic treatment options.
Cardiometabolic, autoimmune, and neurologic disorders
Beyond oncology, the research portfolio includes atherosclerotic cardiovascular disease, myocardial infarction, heart failure, stroke, myasthenia gravis, multiple sclerosis, and autoimmune hemolytic anemia.
- Cardiovascular disease
- Myasthenia gravis
- Multiple sclerosis
Additional therapeutic focus includes amyloidosis, asthma, and other immune-mediated or chronic inflammatory conditions.
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