Justyna W. K.
- Country
- Germany
- Department
- Fachklinik Löwenstein, Med. Klinik I, Pneumologie
Research Overview
Data & Insights
Has run more than one trial at 0 of 13 partner sites.
Specializations
Non‑Small Cell Lung Cancer
Focused on therapeutic strategies for non‑small cell lung cancer across stages, emphasizing immunotherapy and targeted agents.
- PD‑L1 inhibition
- KRAS G12C targeting
- EGFR uncommon mutations
- Adjuvant immunotherapy
- Combination chemo‑immunotherapy
Clinical activity includes advanced, metastatic, and locally advanced disease.
Small Cell Lung Cancer & Thoracic Oncology
Investigates treatment options for small cell lung cancer and related thoracic malignancies, integrating novel antibody‑drug conjugates and checkpoint blockade.
- Tiragolumab plus atezolizumab
- Anti‑TIGIT strategies
- Second‑line chemotherapy alternatives
- Biomarker‑driven patient selection
- Maintenance immunotherapy
Research spans extensive‑stage and limited‑stage disease.
Fibrotic Lung Disease
Addresses progressive fibrotic lung disease including idiopathic pulmonary fibrosis, evaluating inhaled and systemic antifibrotic therapies.
- Inhaled treprostinil
- Long‑term safety assessment
- Disease‑progression endpoints
- Quality‑of‑life measures
- Combination with standard antifibrotics
Focus on chronic progressive phenotypes.
Hematologic Malignancies
Engages in therapeutic development for acute myeloid leukemia, myelodysplastic syndromes, and multiple myeloma, emphasizing targeted and immunomodulatory agents.
- Venetoclax‑based regimens
- IDH1/2 inhibition
- BCL‑2 targeting
- Maintenance therapy post‑transplant
- Minimal residual disease monitoring
Includes both adult and pediatric cohorts.
Cardiovascular & Metabolic Disorders
Explores interventions for cardiovascular risk, notably atherosclerotic cardiovascular disease and elevated Lp(a), through novel lipid‑lowering agents.
- Lipoprotein(a) reduction
- MACE composite outcomes
- Gene‑silencing therapeutics
- Safety in high‑risk populations
- Biomarker‑driven efficacy
Targets patients with established disease and elevated biomarkers.
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