Justine S.
- Country
- France
- Department
- Hematology
Research Overview
Data & Insights
Has run more than one trial at 0 of 33 partner sites.
Specializations
Myeloid Neoplasms
Focuses on Acute Myeloid Leukemia and related disorders, including genetic subtypes and therapeutic strategies.
- IDH1‑mutated AML
- FLT3‑mutated AML
- Myelodysplastic syndrome
- Blastic plasmacytoid dendritic cell neoplasm
- Acute venous thromboembolism in leukemia patients
Emphasis on targeted agents and combination regimens for high‑risk disease.
Acute Lymphoblastic Leukemia
Investigates Philadelphia‑negative B‑cell ALL and Philadelphia‑positive B‑ALL with novel immunotherapies.
- Blinatumomab‑based frontline therapy
- Isatuximab in T‑ALL
- Ponatinib combined with immunotherapy
- MRD‑guided treatment adaptation
- Allogeneic stem‑cell transplantation criteria
Aims to improve survival and reduce transplant reliance.
Multiple Myeloma
Addresses therapeutic options for multiple myeloma in relapsed and frail populations.
- Daratumumab‑lenalidomide‑dexamethasone fixed‑duration regimen
- Elranatamab plus lenalidomide maintenance
- Subcutaneous daratumumab administration
- MRD‑driven consolidation
- Combination with anti‑CD38 antibodies
Focus on balancing efficacy with tolerability.
Non‑Small Cell Lung Cancer
Explores treatment pathways for non‑small cell lung cancer including immunotherapy and anti‑angiogenic agents.
- Atezolizumab with platinum‑pemetrexed
- Bevacizumab addition for EGFR/ALK‑mutated disease
- Biomarker‑guided ctDNA surveillance
- Combination with targeted therapies
- Second‑line immunotherapy sequencing
Seeks to extend progression‑free survival in molecularly defined cohorts.
Hematopoietic Stem Cell Transplantation
Focuses on peri‑transplant management and complications such as infection and thrombosis.
- Graft‑versus‑host disease prophylaxis
- Oral vancomycin for C. difficile prevention
- Cancer‑associated thrombosis prophylaxis
- Management of pure red cell aplasia
- Immunomodulation after traumatic brain injury
Integrates prophylactic and therapeutic strategies to improve post‑transplant outcomes.
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