Justine G.
- Country
- France
- Department
- Onco-hématologie pédiatrique
Research Overview
- Phase 3 Double-Blind Study of Ivosidenib in Adults with IDH1-Mutant Locally Advanced or Metastatic Conventional Chondrosarcoma
- Efficacy of Pembrolizumab and Cabozantinib in Advanced Undifferentiated Pleomorphic Sarcoma, Osteosarcoma, and Ewing Sarcoma: A Clinical Trial Evaluation
- Evaluation of Adjuvant Doxorubicin and Trabectedin Chemotherapy in High-Risk Localized Resected Uterine Leiomyosarcoma
Data & Insights
Has run more than one trial at 10 of 62 partner sites.
Specializations
Thoracic Oncology and Solid Tumors
Clinical research activity is centered on non-small cell lung cancer, including adjuvant, locally advanced, metastatic, and biomarker-defined disease, with related interest in other thoracic malignancies and broader solid tumor care.
- Non-small cell lung cancer
- Small cell lung cancer
- Advanced solid tumors
- Thoracic malignancies
Therapeutic focus includes immunotherapy, targeted therapy, and combination strategies for advanced cancer management.
Hematologic Malignancies
The investigator is involved in studies across acute and chronic blood cancers, with emphasis on treatment innovation in leukemia, lymphoma, and related marrow disorders.
- Acute lymphoblastic leukemia
- Acute myeloid leukemia
- Diffuse large B-cell lymphoma
- Multiple myeloma
Research interests also extend to myelodysplastic syndrome, chronic lymphocytic leukemia, and refractory or relapsed hematologic disease.
Autoimmune, Inflammatory, and Neuromuscular Diseases
There is strong involvement in immune-mediated disorders, particularly systemic lupus erythematosus, rheumatoid arthritis, Sjögren’s syndrome, and systemic sclerosis, alongside inflammatory muscle and nerve conditions.
- Systemic lupus erythematosus
- Rheumatoid arthritis
- Sjögren’s syndrome
- Idiopathic inflammatory myopathies
Additional interest includes vasculitis, myasthenia gravis, multiple sclerosis, and peripheral neuropathy.
Pulmonary, Critical Care, and Infectious Diseases
Clinical trial activity covers respiratory and intensive care conditions, with attention to asthma, chronic obstructive pulmonary disease, interstitial lung disease, and severe infection-related complications.
- Severe asthma
- Interstitial lung disease
- Chronic pulmonary aspergillosis
- Sepsis
Research also includes pulmonary arterial hypertension, bronchiectasis, pneumonia, and intensive care medicine.
Neurology, Neurodegeneration, and Rare Diseases
The investigator is active in neurological disorders spanning Alzheimer’s disease, Parkinson’s disease, epilepsy, and demyelinating disease, with additional work in selected rare pediatric and adult conditions.
- Alzheimer’s disease
- Parkinson’s disease
- Epilepsy
- Spinal muscular atrophy
Further therapeutic interest includes stroke, migraine, developmental and epileptic encephalopathies, and rare tumors.
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