Jurjan A.
- Country
- The Netherlands
- Department
- Pulmonary Medicine
Research Overview
- Efficacy and Safety of IKT-001 in Adults with WHO Group 1 Pulmonary Arterial Hypertension: An Adaptive, Randomized, Double-Blind, Placebo-Controlled Trial
- Evaluation of Riociguat Discontinuation Post-Balloon Pulmonary Angioplasty in Chronic Thromboembolic Pulmonary Hypertension: A Randomized Controlled Non-Inferiority Trial
Data & Insights
Has run more than one trial at 1 of 40 partner sites.
Specializations
Pulmonary Medicine and Respiratory Disease
Clinical activity centers on lung cancer, interstitial lung disease, idiopathic pulmonary fibrosis, pulmonary arterial hypertension, and chronic thromboembolic pulmonary hypertension, reflecting a strong focus on diseases of the airways, lung parenchyma, and pulmonary vasculature.
- Non-small cell lung cancer
- Small cell lung cancer
- Bronchiectasis
- Chronic lung disease
- Pulmonary hypertension
Research interests also extend to advanced thoracic malignancies and treatment-relevant respiratory complications, including bronchiectasis with chronic pseudomonas aeruginosa colonization and progressive pulmonary fibrosis.
Thoracic Oncology and Solid Tumor Treatment
The investigator is involved in clinical research across a broad spectrum of cancers, with particular emphasis on thoracic oncology and other solid tumors, including disease settings that require multimodal or targeted treatment strategies.
- Non-small cell lung cancer
- Esophageal cancer
- Pancreatic cancer
- Colorectal cancer
- Head and neck squamous cell carcinoma
Additional activity includes melanoma, urothelial cancer, and gastric cancer, indicating involvement in oncology programs that span both localized and metastatic disease.
Hematologic Malignancies and Cellular Therapies
Clinical research includes multiple blood cancers and related treatment domains, with attention to lymphoma, leukemia, and multiple myeloma, as well as emerging approaches in cellular therapy.
- Diffuse large B-cell lymphoma
- Hodgkin lymphoma
- Chronic lymphocytic leukemia
- Acute myeloid leukemia
- Multiple myeloma
Research interests also cover myelodysplastic syndromes, mantle cell lymphoma, and relapsed or refractory hematologic disease, supporting work in advanced hematology and immune-based treatment options.
Immune-Mediated Disease and Autoimmunity
The investigator is active in inflammatory and autoimmune conditions, including rheumatoid arthritis, systemic lupus erythematosus, systemic sclerosis, and Crohn's disease, with additional interest in organ-specific immune disorders.
- Ulcerative colitis
- Atopic dermatitis
- Primary sclerosing cholangitis
- Myositis
- Vasculitis
Other areas include eosinophilic esophagitis, psoriasis, and immune-mediated thrombocytopenia, showing engagement with chronic inflammatory disease management.
Cardiometabolic, Neurologic, and Rare Disease Interests
Broader clinical involvement spans cardiovascular disease, stroke, heart failure, diabetes, and selected neurologic disorders, alongside rare inherited and metabolic conditions.
- Atherosclerotic cardiovascular disease
- Atrial fibrillation
- Ischemic stroke
- Multiple sclerosis
- Primary kidney disease
Research coverage also includes familial hypercholesterolemia, amyloidosis, and genetic cardiomyopathy, reflecting participation in therapeutic areas with significant unmet clinical need.
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