Juraj Ď.
- Country
- Slovakia
- Department
- Gastroenterologická ambulancia
Research Overview
- Evaluation of Long-Term Safety and Efficacy of Upadacitinib in Patients with Ulcerative Colitis: A Phase 3 Multicenter Extension Study
- Efficacy and Safety Evaluation of RO7790121 Induction Therapy in Moderately to Severely Active Ulcerative Colitis: A Phase III Multicenter Double-Blind Placebo-Controlled Study
- Efficacy and Safety of RO7790121 Induction Therapy in Moderately to Severely Active Crohn's Disease: A Phase III, Multicenter, Double-Blind, Placebo-Controlled Study
Data & Insights
Has run more than one trial at 67 of 208 partner sites.
Specializations
Inflammatory Bowel Disease
Clinical research activity includes Crohn's disease and ulcerative colitis, with attention to active disease control, remission, and long-term treatment in patients with moderate to severe gastrointestinal inflammation.
- Moderately to severely active Crohn's disease
- Moderate to severely active ulcerative colitis
- Maintenance therapy in inflammatory bowel disease
The therapeutic focus also extends to sustained disease management in patients who require ongoing care for chronic intestinal inflammation.
Advanced Gastrointestinal and Hepatic-Adjacent Oncology
Research involvement covers advanced solid tumors and malignancies associated with non-small cell lung cancer, metastatic breast cancer, and prostate cancer, reflecting interest in systemic treatment options for difficult-to-treat cancers.
- Advanced/metastatic breast cancer
- Non-small cell lung cancer
- Metastatic castration-resistant prostate cancer
Additional work includes tumor settings marked by CDK4 or CCND1 amplification and other advanced malignancies requiring novel oncologic approaches.
Dermatologic and Immune-Mediated Disorders
Clinical trial activity includes immune-driven skin diseases such as atopic dermatitis, hidradenitis suppurativa, and chronic spontaneous urticaria, with emphasis on symptom control and longer-term disease suppression.
- Atopic dermatitis
- Hidradenitis suppurativa
- Chronic spontaneous urticaria
The therapeutic landscape also includes inflammatory skin disease management in adolescent and adult populations.
Maternal-Fetal and Hematologic Conditions
Research interests extend to fetal and neonatal alloimmune thrombocytopenia, highlighting involvement in pregnancy-related hematologic risk and prevention of severe neonatal complications.
- Fetal and neonatal alloimmune thrombocytopenia
- At-risk pregnancy care
- Neonatal thrombocytopenia prevention
This area reflects a therapeutic focus on rare maternal-fetal disorders with potential impact on perinatal outcomes.
Cancer-Related Supportive Care and Cachexia
Clinical research also includes cancer cachexia and associated weight loss in advanced malignancy, with interest in supportive oncology and symptom burden reduction.
- Cancer cachexia
- Body weight loss in cancer
- Appetite-related symptom management
The therapeutic domain covers supportive interventions for patients with advanced cancer and systemic metabolic decline.
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