Julien H.
- Country
- France
- Department
- service oncologie médicale
Research Overview
- Phase II Randomized Study of FOLFIRI Plus Zimberelimab and Domvanalimab Versus FOLFIRI in Patients With Second-Line Metastatic Gastro-Enteropancreatic or Unknown Origin Neuroendocrine Carcinoma
- Phase III Trial of BI 764532 Plus Carboplatin and Etoposide Versus Carboplatin and Etoposide in Previously Untreated DLL3-Positive Advanced Extrapulmonary Neuroendocrine Carcinoma
- Phase II Dose‑Finding and Efficacy Study of Intratumoral Getacatetide (CY‑101) in Patients with Locally Advanced or Metastatic Adrenocortical Carcinoma
Data & Insights
Has run more than one trial at 43 of 178 partner sites.
Specializations
Endocrine Oncology
The investigator specializes in treating RET-mutant medullary thyroid cancer, demonstrating expertise in targeted therapies for rare thyroid malignancies. Their research encompasses novel therapeutic approaches using kinase inhibitors for advanced thyroid conditions.
- Thyroid Cancer Management
- RET Mutation Testing
- Targeted Therapy Development
Their work includes evaluating comparative treatment efficacy in progressive thyroid cancer cases.
Gastrointestinal Neuroendocrine Tumors
The investigator focuses on treating metastatic gastroenteropancreatic neuroendocrine carcinomas, with particular attention to grade 3 poorly differentiated cases. Their expertise extends to developing treatment protocols for tumors of unknown primary origin.
- Advanced Chemotherapy Protocols
- Neuroendocrine Cancer Treatment
- Metastatic Disease Management
Their research evaluates innovative chemotherapy combinations for advanced neuroendocrine tumors.
Rare Tumor Syndromes
The investigator's expertise encompasses multiple rare conditions including pheochromocytoma, paraganglioma, and von Hippel-Lindau disease-associated tumors. They specialize in treating complex cases involving HIF-2α genetic alterations.
- Genetic Tumor Syndromes
- Molecular Targeted Therapies
- Pancreatic Neuroendocrine Tumors
Their work involves developing targeted treatments for rare tumor types with specific genetic profiles.
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