Julian W.
- Country
- Germany
- Department
- Klinik für Innere Medizin I (Kardiologie, Angiologie, Internistische Intensivmedizin)
Research Overview
- Phase III Randomized Double‑Blind Trial of Elecoglipron (AZD5004) on Cardiovascular Mortality and Hospitalization in Adults with HFpEF or HFmrEF on Background Dapagliflozin
- Efficacy and Safety Evaluation of Omecamtiv Mecarbil in Patients with Heart Failure and Severely Reduced Ejection Fraction: A Randomized, Double-Blind, Placebo-Controlled Trial
- Evaluation of Empagliflozin Continuation Versus Placebo in Patients with Acute Decompensated Heart Failure on SGLT2 Inhibitor Therapy
Data & Insights
Has run more than one trial at 62 of 330 partner sites.
Specializations
Haematological malignancies
Clinical research activity includes a strong focus on acute myeloid leukemia, myelodysplastic syndrome, chronic myeloid leukemia, multiple myeloma, and aggressive lymphoma entities, with interest in relapsed, refractory, and transplant-related settings.
- Acute myeloid leukemia
- Myelodysplastic syndrome
- Multiple myeloma
- Diffuse large B-cell lymphoma
- Chronic myeloid leukemia
Additional activity extends to allogeneic stem cell transplantation, graft-versus-host disease, and hematopoietic stem cell transplantation support strategies.
Solid tumours and genitourinary oncology
The investigator is involved in clinical research across renal cell carcinoma, urothelial carcinoma, prostate cancer, bladder cancer, and lung cancer, with emphasis on advanced and metastatic disease management.
- Renal cell carcinoma
- Urothelial carcinoma
- Prostate cancer
- Non-small cell lung cancer
- Head and neck squamous cell carcinoma
Therapeutic interests also include immune checkpoint therapy, targeted therapy, and treatment strategies for gastroesophageal and ovarian cancers.
Gastroenterology and liver disease
Research activity covers inflammatory bowel disease, including Crohn’s disease and ulcerative colitis, alongside liver cirrhosis, acute-on-chronic liver failure, and hepatorenal syndrome.
- Crohn’s disease
- Ulcerative colitis
- Liver cirrhosis
- Acute-on-chronic liver failure
- Hepatorenal syndrome
Additional therapeutic interest is seen in post-gastrectomy care and albumin-based management in chronic liver disease.
Cardiovascular and renal medicine
The clinical portfolio includes heart failure, atherosclerotic cardiovascular disease, atrial fibrillation, acute myocardial infarction, and cardiorenal syndrome, with related work in chronic kidney disease and acute kidney injury.
- Heart failure
- Atherosclerotic cardiovascular disease
- Atrial fibrillation
- Chronic kidney disease
- Acute kidney injury
Therapeutic domains also include cardiovascular risk reduction, stroke prevention, and protection against cardiac surgery-associated kidney injury.
Neurology, immunology, and inflammatory disease
Additional trial involvement spans multiple sclerosis, amyotrophic lateral sclerosis, migraine, systemic lupus erythematosus, and systemic sclerosis, reflecting interest in autoimmune and neurodegenerative disorders.
- Multiple sclerosis
- Amyotrophic lateral sclerosis
- Migraine
- Systemic lupus erythematosus
- Systemic sclerosis
Research also includes myasthenia gravis, rheumatoid arthritis, and other immune-mediated inflammatory diseases.
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