Julia R.
- Country
- Germany
- Department
- Frauenklinik
Research Overview
- CAPTOR-BC: COMPREHENSIVE ANALYSIS OF SPATIAL, TEMPORAL AND MOLECULAR PATTERNS OF RIBOCICLIB EFFICACY AND RESISTANCE IN ADVANCED BREAST CANCER PATIENTS
- A PHASE III, RANDOMIZED, OPEN-LABEL STUDY EVALUATING THE EFFICACY AND SAFETY OF GIREDESTRANT IN COMBINATION WITH PHESGO VERSUS PHESGO AFTER INDUCTION THERAPY WITH PHESGO+TAXANE IN PATIENTS WITH PREVIOUSLY UNTREATED HER2-POSITIVE, ESTROGEN RECEPTOR-POSITIVE LOCALLY-ADVANCED OR METASTATIC BREAST CANCER
- Efficacy and Safety of Giredestrant vs. Fulvestrant with CDK4/6 Inhibitor in ER+ HER2- Advanced Breast Cancer Resistant to Endocrine Therapy
Data & Insights
Has run more than one trial at 269 of 583 partner sites.
Specializations
Breast Cancer and Gynecologic Oncology
Clinical work is centered on breast cancer, with interest in hormone receptor-positive, HER2-negative, and HER2-positive disease, including early-stage, locally advanced, metastatic, and high-risk settings. The portfolio also includes cervical cancer and ovarian cancer.
- Hormone receptor-positive breast cancer
- HER2-negative and HER2-positive breast cancer
- Triple-negative breast cancer
- Cervical cancer
- Ovarian cancer
Therapeutic interest extends to endocrine-based treatment strategies, antibody-based combinations, and approaches aimed at reducing recurrence risk in early and advanced disease.
Hematologic Malignancies
Research activity covers a broad spectrum of hematologic malignancies, including acute myeloid leukemia, acute lymphoblastic leukemia, chronic lymphocytic leukemia, and multiple aggressive and indolent lymphomas. The work also includes myelodysplastic syndromes and related marrow disorders.
- Acute myeloid leukemia
- Acute lymphoblastic leukemia
- Chronic lymphocytic leukemia
- Diffuse large B-cell lymphoma
- Hodgkin lymphoma and mantle cell lymphoma
Therapeutic focus includes immunotherapy, targeted agents, transplant-related treatment concepts, and risk-adapted strategies for adult and pediatric blood cancers.
Thoracic and Solid Tumor Oncology
Clinical interests include non-small cell lung cancer, small cell lung cancer, prostate cancer, head and neck squamous cell carcinoma, glioblastoma, medulloblastoma, and selected sarcomas and germ cell tumors.
- Non-small cell lung cancer
- Small cell lung cancer
- Prostate cancer
- Glioblastoma and medulloblastoma
- Head and neck cancer and sarcoma
The therapeutic landscape includes checkpoint inhibition, targeted therapy, and multimodal treatment approaches for locally advanced and metastatic solid tumors.
Cardiometabolic and Liver Disease
Research involvement extends to heart failure, pulmonary arterial hypertension, hypertension, type 2 diabetes, and chronic kidney disease, alongside liver-focused conditions such as metabolic dysfunction-associated steatotic liver disease, metabolic dysfunction-associated steatohepatitis, non-alcoholic steatohepatitis, liver cirrhosis, and hepatocellular carcinoma.
- Heart failure and hypertension
- Pulmonary arterial hypertension
- Metabolic dysfunction-associated steatotic liver disease
- Metabolic dysfunction-associated steatohepatitis
- Hepatocellular carcinoma
Therapeutic attention is directed toward cardiovascular risk reduction, pulmonary vascular disease, and disease-modifying strategies for progressive metabolic liver disorders.
Neurology, Ophthalmology, and Rare Disorders
Additional clinical interests include Alzheimer’s disease, Parkinson’s disease, major depressive disorder, chronic pain, neuropathies, and cognitive impairment. The portfolio also features Fuchs endothelial corneal dystrophy, neurotrophic keratopathy, diabetic macular edema, and acute retinal artery occlusion, as well as rare conditions such as hemophilia and amyloid cardiomyopathy.
- Alzheimer’s disease and Parkinson’s disease
- Chronic pain and neuropathy
- Corneal and retinal disease
- Hemophilia
- Transthyretin amyloid cardiomyopathy
Therapeutic interests span neurodegenerative care, pain management, vision preservation, and treatment development for uncommon hereditary and multisystem disorders.
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