Juan Jose L.
- Country
- Spain
- Department
- Neurologia
Research Overview
- Efficacy of Pegipanermin (XPro1595) in Early Alzheimer's Disease with Inflammatory Biomarkers: A Randomized, Double-Blind, Placebo-Controlled Trial
- Efficacy, Safety, and Tolerability of Bepranemab in Prodromal to Mild Alzheimer's Disease: A Placebo-Controlled Study with Open-Label Extension
- Evaluation of Intravenous Prasinezumab Efficacy and Safety in Early Parkinson's Disease: A Phase IIb Randomized, Double-Blind, Placebo-Controlled Multicenter Study
Data & Insights
Has run more than one trial at 71 of 200 partner sites.
Specializations
Stroke and cerebrovascular disease
Juan López Lozano is involved in clinical research on acute ischemic stroke, high-risk transient ischemic attack, and secondary prevention after recent cerebrovascular events, with attention to functional recovery and antithrombotic strategies.
- Acute ischemic stroke
- Transient ischemic attack
- Stroke prevention
His therapeutic interests in neurology include interventions aimed at reducing recurrent ischemic events and improving post-stroke outcomes.
Alzheimer’s disease and cognitive disorders
His research landscape includes multiple studies in Alzheimer’s disease, from early and prodromal stages to more advanced cognitive impairment, as well as related behavioral symptoms such as agitation.
- Early Alzheimer’s disease
- Mild cognitive impairment
- Agitation associated with Alzheimer’s disease
He is also involved in work addressing cognitive decline and neuropsychiatric symptoms in degenerative brain disease.
Movement disorders and multiple sclerosis
Juan López Lozano contributes to clinical trials in Parkinson’s disease, including early-stage disease, alongside research in relapsing forms of multiple sclerosis focused on central nervous system inflammation and disease control.
- Early Parkinson’s disease
- Relapsing multiple sclerosis
- Motor progression
These activities reflect a therapeutic focus on chronic neurodegenerative and immune-mediated neurological disorders.
Headache and migraine
He is active in studies of chronic migraine, episodic migraine, and migraine attacks with or without aura, covering both prevention and acute treatment approaches.
- Chronic migraine
- Episodic migraine
- Acute migraine treatment
His involvement extends across disabling headache disorders that affect long-term neurological quality of life.
Metabolic, gastrointestinal, and hematologic conditions
His broader clinical portfolio includes trials in obesity, overweight, type 2 diabetes, ulcerative colitis, chronic immune thrombocytopenia, and selected hematologic malignancies.
- Obesity and weight management
- Type 2 diabetes mellitus
- Ulcerative colitis
He also participates in research on multiple myeloma, mantle cell lymphoma, and hypercholesterolemia, indicating interest in both chronic disease management and oncology-related therapeutics.
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