Jozsef L.
- Country
- Hungary
- Department
- 3615: I. Belgyogyaszati Osztaly - Kardiologia es Angiologia
Research Overview
- Inclisiran for Prevention of Major Adverse Cardiovascular Events in High-Risk Primary Prevention Patients with Atherosclerotic Cardiovascular Disease
- Efficacy, Safety, and Tolerability of AZD0780 in Dyslipidemia: A Phase IIb Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Study
- Phase 3 Randomized Study Comparing Asundexian and Apixaban for Stroke Prevention in Atrial Fibrillation Patients at Risk
Data & Insights
Has run more than one trial at 833 of 1524 partner sites.
Specializations
Cardiovascular medicine
Clinical research activity is centered on atherosclerotic cardiovascular disease, high cardiovascular risk, hypertension, dyslipidemia, and prevention of major adverse cardiovascular events. The portfolio also includes treatment domains involving heart failure, atrial fibrillation, and stroke prevention, with attention to both primary and secondary cardiovascular risk reduction.
- ASCVD
- Heart failure
- Atrial fibrillation
- Stroke prevention
Research involvement extends to cardiometabolic risk modification and inflammatory cardiovascular disease, reflecting interest in therapies targeting lipid lowering, thrombosis prevention, and broader vascular protection.
Retinal and macular disease
The investigator is active in ophthalmic trials focused on diabetic retinopathy, diabetic macular edema, retinal vein occlusion, wet age-related macular degeneration, geographic atrophy, and macular neovascularization. This work spans conditions associated with central vision loss and chronic retinal degeneration.
- Diabetic macular edema
- Age-related macular degeneration
- Geographic atrophy
- Retinal vascular disease
Therapeutic interest includes intravitreal and ocular approaches designed to preserve visual function and address progressive retinal injury.
Neurology and neuroimmunology
Clinical trial participation includes multiple sclerosis, including relapsing multiple sclerosis and primary progressive multiple sclerosis, along with studies in generalized myasthenia gravis. The portfolio reflects engagement with immune-mediated neurological disorders requiring long-term disease control.
- Multiple sclerosis
- Primary progressive multiple sclerosis
- Relapsing multiple sclerosis
- Generalized myasthenia gravis
Research interest also covers therapies aimed at reducing relapse burden, slowing progression, and sustaining neurological function in chronic autoimmune disease.
Oncology and genitourinary disease
The investigator is involved in trials for prostate cancer, including metastatic castration-sensitive prostate cancer, biochemically recurrent prostate cancer, and high-risk recurrent disease. These studies align with therapeutic strategies in hormone-sensitive and advanced genitourinary oncology.
- Prostate cancer
- Metastatic castration-sensitive disease
- Biochemical recurrence
- High-risk recurrence
Additional interest includes management of complicated urinary tract infection and acute pyelonephritis, broadening the therapeutic scope into serious infectious disease.
Respiratory and metabolic disorders
Clinical research also covers severe asthma and obesity, alongside related cardiometabolic conditions. This indicates involvement in therapies addressing airway inflammation, symptom control, and metabolic risk.
- Severe asthma
- Obesity
- Cardiometabolic disease
The investigator’s portfolio further includes conditions such as acquired blepharoptosis, showing participation in selected non-systemic therapeutic areas.
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