Joseph E.
- Country
- France
- Department
- 75
Research Overview
- Effect of One-Year versus One-Month Dual Antiplatelet Therapy Comprising Aspirin and Clopidogrel on Outcomes in Patients with Chronic Limb-Threatening Ischemia After Revascularization
- Evaluation of Laroprovstat (AZD0780) on Major Adverse Cardiovascular Events in Patients with Atherosclerotic Cardiovascular Disease or High ASCVD Risk
Data & Insights
Has run more than one trial at 9 of 349 partner sites.
Specializations
Neurovascular Disease and Stroke
Clinical research activity includes acute and secondary prevention strategies in ischemic stroke, intracerebral haemorrhage, transient ischemic attack, and severe cerebrovascular events linked to large-vessel occlusion and brain aneurysm care.
- Acute ischemic stroke
- Intracerebral haemorrhage
- Stroke prevention
- Brain aneurysm management
Therapeutic interests also extend to post-stroke recovery, neurological deterioration in the acute setting, and vascular risk reduction.
Thoracic Oncology and Solid Tumors
Investigational work is strongly centered on non-small cell lung cancer, with additional involvement in small cell lung cancer, head and neck cancer, colorectal cancer, ovarian cancer, and prostate cancer.
- Non-small cell lung cancer
- Prostate cancer
- Ovarian cancer
- Head and neck squamous cell carcinoma
The oncology portfolio also includes targeted therapy, immunotherapy, and treatment approaches for advanced or metastatic disease.
Pulmonary Medicine and Interstitial Lung Disease
Research activity covers chronic and progressive lung disorders, including idiopathic pulmonary fibrosis, progressive pulmonary fibrosis, interstitial lung disease, sarcoidosis, and chronic lung allograft dysfunction.
- Idiopathic pulmonary fibrosis
- Progressive pulmonary fibrosis
- Interstitial lung disease
- Lung transplant rejection
Additional interests include pulmonary hypertension, respiratory failure, and fibrotic lung disease associated with systemic conditions.
Cardiovascular, Thrombotic, and Metabolic Disorders
Clinical interests include heart failure, cardiac arrest, atrial and vascular disease, anticoagulation management, and prevention of thromboembolic complications in high-risk settings.
- Heart failure
- Cardiac arrest
- Peripheral arterial disease
- Anticoagulation reversal
Metabolic and renal interests also appear through type 2 diabetes, chronic kidney disease, obesity, and lipid-lowering therapy.
Inflammatory, Autoimmune, and Neuropsychiatric Disorders
Research involvement spans rheumatoid arthritis, Crohn's disease, myasthenia gravis, sarcoidosis, and gout, alongside psychiatric conditions such as major depressive disorder, treatment-resistant depression, schizophrenia, and anxiety disorders.
- Rheumatoid arthritis
- Myasthenia gravis
- Treatment-resistant depression
- Gout
Other therapeutic interests include autoimmune lung disease, epilepsy, and disorders affecting quality of life in chronic illness.
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