Josefina M.
- Country
- Portugal
- Department
- Infectiology Department
Research Overview
- A Phase 3b Study Comparing Dolutegravir/Lamivudine to Bictegravir/Emtricitabine/Tenofovir Alafenamide in Antiretroviral-Naive Adults with HIV
- Evaluation of Efficacy, Safety, and Tolerability of Switching from Bictegravir/Emtricitabine/Tenofovir Alafenamide to Dolutegravir/Lamivudine in Virologically Suppressed HIV Patients Aged 50+
- Phase 3b Randomized Study on Efficacy and Safety of Cabotegravir and Rilpivirine in HIV-1 Patients with Viremia and Suboptimal Oral ART Response
Data & Insights
Has run more than one trial at 52 of 121 partner sites.
Specializations
Infectious Diseases and Antiretroviral Therapy
Josefina Mendez is involved in clinical research on HIV infection and HIV-1, with attention to treatment maintenance, virologic suppression, and regimen switching in adults living with chronic infection.
- HIV treatment optimization
- Virologic suppression
- Antiretroviral therapy
Her work in infectiology also extends to Clostridioides difficile infection and broader infectious disease management in hospital-based care.
Autoimmune and Inflammatory Skin Disease
Her clinical research includes a strong focus on atopic dermatitis, hidradenitis suppurativa, psoriasis, vitiligo, prurigo nodularis, and cutaneous lupus erythematosus, reflecting sustained involvement in immune-mediated dermatologic disease.
- Atopic dermatitis
- Hidradenitis suppurativa
- Psoriasis
- Cutaneous lupus erythematosus
She is also engaged in studies relevant to subacute cutaneous lupus erythematosus, systemic lupus erythematosus, and other chronic inflammatory skin conditions.
Rheumatologic and Systemic Autoimmune Disorders
Josefina Mendez participates in research on systemic lupus erythematosus, lupus nephritis, Sjögren’s syndrome, idiopathic inflammatory myopathy, and eosinophilic granulomatosis with polyangiitis, supporting therapeutic development in multisystem autoimmune disease.
- Systemic lupus erythematosus
- Lupus nephritis
- Sjögren’s syndrome
- Idiopathic inflammatory myopathy
Her portfolio also includes myasthenia gravis and other immune-mediated disorders affecting neuromuscular and systemic function.
Neurology and Neuroinflammatory Disease
Her trial activity covers multiple sclerosis, primary progressive multiple sclerosis, relapsing multiple sclerosis, epilepsy, migraine, Parkinson’s disease, and frontotemporal dementia, indicating broad interest in chronic neurologic and neurodegenerative conditions.
- Multiple sclerosis
- Epilepsy
- Migraine
- Parkinson’s disease
She is also involved in studies of myelin oligodendrocyte glycoprotein antibody-associated disease and spinocerebellar ataxia.
Gastroenterology, Nephrology, and Cardiometabolic Conditions
Her clinical research landscape includes Crohn’s disease, ulcerative colitis, eosinophilic esophagitis, chronic kidney disease, proteinuria, heart failure, and pulmonary arterial hypertension, spanning digestive, renal, and cardiovascular therapeutic areas.
- Crohn’s disease
- Ulcerative colitis
- Chronic kidney disease
- Heart failure
She is also linked to research in transthyretin amyloidosis, atherosclerotic cardiovascular disease, and obesity.
Related Investigators
Researchers in similar fields or departments
Want to know more about this investigator?
We can share extended profile information and contact details.
Is something out of date?
Tell us what needs correcting and we'll update this profile.