Jose Tomas O. P.
- Country
- Spain
- Department
- Cardiology
Research Overview
- Evaluation of Sacubitril/Valsartan on Systolic Function in Transthyretin Cardiac Amyloidosis and Heart Failure with Reduced Ejection Fraction
- TRITON-CM: A Phase 3 Global, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Nucresiran in Patients with Transthyretin-Mediated Amyloidosis with Cardiomyopathy (ATTR amyloidosis with cardiomyopathy)
Data & Insights
Has run more than one trial at 5 of 114 partner sites.
Specializations
Cardiovascular Medicine
Jose Tomas Ortiz Perez is involved in clinical research focused on cardiology, with particular interest in acute coronary syndrome, myocardial infarction, atrial fibrillation, heart failure, and atherosclerotic cardiovascular disease. His trial portfolio also includes work in hypertrophic cardiomyopathy, pulmonary hypertension, and cardiac amyloidosis.
- Acute myocardial infarction
- Heart failure
- Atrial fibrillation
- Hypertrophic cardiomyopathy
- Transthyretin cardiac amyloidosis
His research landscape reflects a strong therapeutic emphasis on cardiovascular risk reduction, thromboembolic disease, and treatment strategies for structural and inflammatory heart conditions.
Oncology and Hematologic Malignancies
His clinical trial activity spans a broad range of solid tumors and blood cancers, including breast cancer, non-small cell lung cancer, prostate cancer, urothelial carcinoma, ovarian cancer, colorectal cancer, melanoma, and pancreatic cancer. He is also involved in studies of multiple myeloma, acute myeloid leukemia, lymphoma, and myelodysplastic syndromes.
- Breast cancer
- Non-small cell lung cancer
- Prostate cancer
- Multiple myeloma
- Acute myeloid leukemia
His therapeutic interests include precision oncology, immuno-oncology, and targeted treatment approaches across advanced and metastatic malignancies.
Autoimmune and Inflammatory Disorders
He is engaged in research on rheumatoid arthritis, psoriatic arthritis, systemic lupus erythematosus, Crohn's disease, ulcerative colitis, and hidradenitis suppurativa. Additional interest extends to asthma, atopic dermatitis, and other immune-mediated inflammatory diseases.
- Rheumatoid arthritis
- Psoriatic arthritis
- Systemic lupus erythematosus
- Crohn's disease
- Ulcerative colitis
His work in this area supports therapeutic development for chronic immune dysregulation, mucosal inflammation, and dermatologic inflammatory disease.
Neurology and Neurodegenerative Disease
His research includes Alzheimer's disease, Parkinson's disease, frontotemporal dementia, multiple sclerosis, progressive supranuclear palsy, and focal epilepsy. He is also involved in studies of migraine, narcolepsy, and other central nervous system disorders.
- Alzheimer's disease
- Parkinson's disease
- Frontotemporal dementia
- Multiple sclerosis
- Focal epilepsy
His therapeutic focus in neurology covers cognitive decline, movement disorders, seizure control, and broader neurodegenerative disease management.
Hepatology, Nephrology, and Transplant-Related Care
His clinical research also addresses chronic liver disease, cirrhosis, primary biliary cholangitis, hepatocellular carcinoma, chronic kidney disease, IgA nephropathy, and kidney transplantation. Studies in this domain include transplant-associated complications and organ-specific failure syndromes.
- Chronic liver disease
- Primary biliary cholangitis
- Hepatocellular carcinoma
- Chronic kidney disease
- Kidney transplantation
His therapeutic interests include liver and kidney preservation, transplant medicine, and management of advanced organ dysfunction.
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