Jose Maria O. S.
- Country
- Spain
- Department
- Servicio de Dermatologia
Research Overview
- Phase 3 Extension Study of Long-Term Safety and Efficacy of Remibrutinib in Adults With Moderate to Severe Hidradenitis Suppurativa
- Phase 3 Multicenter Randomized Double-Blind Placebo-Controlled Trial Evaluating Lutikizumab Efficacy and Safety in Moderate to Severe Hidradenitis Suppurativa
- Efficacy and Safety Evaluation of Subcutaneous Sonelokimab in Adults with Moderate to Severe Hidradenitis Suppurativa: A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study
Data & Insights
Has run more than one trial at 112 of 214 partner sites.
Specializations
Dermatologic inflammatory disease
Clinical research activity includes atopic dermatitis, psoriasis, hidradenitis suppurativa, alopecia areata, vitiligo, cutaneous lupus erythematosus, and palmoplantar pustulosis, with interest in immune-mediated skin disease and chronic inflammatory burden.
- Atopic dermatitis
- Psoriasis
- Hidradenitis suppurativa
- Alopecia areata
- Vitiligo
Therapeutic focus extends to targeted anti-inflammatory and immunomodulatory approaches in dermatology, including conditions with significant impact on skin integrity, symptoms, and quality of life.
Cutaneous oncology and melanoma
Research involvement covers melanoma, cutaneous squamous cell carcinoma, actinic keratosis, and other skin cancer settings, including advanced, unresectable, resected, and metastatic disease.
- Melanoma
- Cutaneous squamous cell carcinoma
- Actinic keratosis
- Advanced melanoma
- Skin cancer
The therapeutic landscape includes immunotherapy, adjuvant treatment strategies, and approaches for recurrent or refractory cutaneous malignancies.
Gastrointestinal and hepatology disorders
Investigator activity includes non-alcoholic steatohepatitis, alcohol-related liver disease, chronic hepatitis B, chronic hepatitis C, hepatocellular carcinoma, primary biliary cholangitis, and hepatic encephalopathy.
- Non-alcoholic steatohepatitis
- Chronic hepatitis B
- Chronic hepatitis C
- Hepatocellular carcinoma
- Hepatic encephalopathy
Therapeutic interest spans liver inflammation, viral hepatitis, portal-systemic complications, and malignancy arising in chronic liver disease.
Solid tumors and thoracic oncology
Clinical trial involvement includes non-small cell lung cancer, small cell lung cancer, colorectal cancer, breast cancer, head and neck squamous cell carcinoma, ovarian cancer, and pancreatic cancer.
- Non-small cell lung cancer
- Colorectal cancer
- Breast cancer
- Head and neck squamous cell carcinoma
- Pancreatic cancer
Therapeutic emphasis includes precision oncology, immunotherapy, and treatment strategies for advanced, metastatic, and biomarker-defined solid tumors.
Cardiometabolic, infectious, and autoimmune disease
Research interests also extend to atherosclerotic cardiovascular disease, heart failure, atrial fibrillation, obesity, type 2 diabetes mellitus, HIV infection, pulmonary tuberculosis, and systemic lupus erythematosus.
- Atherosclerotic cardiovascular disease
- Heart failure
- Obesity
- HIV infection
- Systemic lupus erythematosus
Therapeutic activity spans vascular prevention, metabolic disease, antiviral treatment, and immune-mediated systemic disorders.
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