José María F. N.
- Country
- Spain
- Department
- Oncología pediátrica
Research Overview
- Randomized Phase 3 Trial of Venetoclax Added to Fludarabine, High‑Dose Cytarabine, and Gemtuzumab Ozogamicin in Children with Relapsed Acute Myeloid Leukemia
- Evaluation of Quizartinib in Combination with Chemotherapy for Pediatric FLT3-ITD Positive, NPM1 Wild-Type Acute Myeloid Leukemia
- Evaluation of Gemtuzumab Ozogamicin and Drug Combination in Pediatric Acute Myeloid Leukemia: A NOPHO-DB-SHIP Consortium Study
Data & Insights
Has run more than one trial at 59 of 100 partner sites.
Specializations
Pediatric Oncology and Leukemia
José María Fernandez is involved in clinical research across acute lymphoblastic leukemia, acute myeloid leukemia, myelodysplastic syndromes, neuroblastoma, and other childhood and adolescent hematologic malignancies and solid tumors.
- Relapsed and refractory leukemia
- Myelodysplastic neoplasms
- Pediatric lymphoma
- High-risk neuroblastoma
His activity also includes research in molecularly targeted therapy and immunotherapy for pediatric cancers at Hospital Universitario Y Politecnico La Fe.
Thoracic and Solid Tumor Oncology
His trial portfolio includes advanced non-small cell lung cancer, small cell lung cancer, breast cancer, colorectal cancer, renal cell carcinoma, ovarian cancer, and head and neck squamous cell carcinoma.
- Advanced NSCLC
- Small cell lung cancer
- Metastatic breast cancer
- Metastatic colorectal cancer
His research interest extends to targeted anticancer approaches and treatment strategies for metastatic solid tumors.
Immune-Mediated and Inflammatory Disease
José María Fernandez is active in studies of juvenile idiopathic arthritis, psoriatic arthritis, systemic lupus erythematosus, Crohn’s disease, ulcerative colitis, atopic dermatitis, and thyroid eye disease.
- Juvenile idiopathic arthritis
- Inflammatory bowel disease
- Systemic lupus erythematosus
- Atopic dermatitis
His clinical research also covers autoimmune disorders requiring long-term control of inflammatory activity in pediatric and adult populations.
Neurology, Rare Disease, and Genetic Disorders
His research landscape includes epilepsy, migraine, amyotrophic lateral sclerosis, multiple sclerosis, myasthenia gravis, and inherited neuromuscular conditions such as Duchenne muscular dystrophy and spinal muscular atrophy.
- Epileptic disorders
- Neurodegenerative disease
- Muscular dystrophy
- Multiple sclerosis
He also contributes to studies in pediatric neuro-oncology and other genetic rare diseases with unmet therapeutic need.
Transplantation, Hematologic Support, and Cardiometabolic Disease
His clinical research includes graft-versus-host disease, stem cell transplantation, hemophilia, thrombotic thrombocytopenic purpura, heart failure, cardiovascular disease, chronic kidney disease, and obesity.
- Graft-versus-host disease
- Hematologic supportive care
- Heart failure
- Chronic kidney disease
He is also involved in therapeutic studies addressing transplant-related complications and systemic conditions that influence long-term clinical outcomes.
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