Jose G.
- Country
- Spain
- Department
- Nephrology
Research Overview
- Evaluation of Retatrutide (LY3437943) on Renal Function in Overweight or Obese Patients with Chronic Kidney Disease with or without Type 2 Diabetes
- Evaluation of Finerenone and Semaglutide for Albuminuria Reduction in Patients with Chronic Kidney Disease
- Evaluation of Dapagliflozin on Renal and Cardiovascular Outcomes in Patients with Severe Chronic Kidney Disease: A Randomized Controlled Trial
Data & Insights
Has run more than one trial at 7 of 130 partner sites.
Specializations
Oncology
The investigator is engaged in a broad oncology portfolio spanning breast cancer, non-small cell lung cancer, colorectal cancer, ovarian cancer, endometrial cancer, gastric cancer, and urothelial carcinoma, with additional interest in head and neck squamous cell carcinoma, melanoma, and soft tissue sarcoma.
- Solid tumors
- Breast neoplasms
- Thoracic malignancies
- Gynecologic cancers
- Gastrointestinal and genitourinary cancers
Research activity also includes biomarker-defined disease, including HER2-positive and HER2-negative breast cancer, KRAS-mutated tumors, EGFR-altered lung cancer, and BRCA-associated ovarian cancer.
Hematologic malignancies
The investigator is involved in studies of acute myeloid leukemia, myelodysplastic syndrome, myelofibrosis, multiple myeloma, and lymphoid neoplasms, including diffuse large B-cell lymphoma, follicular lymphoma, mantle cell lymphoma, and chronic lymphocytic leukemia.
- Acute leukemias
- Myeloid neoplasms
- B-cell lymphomas
- Plasma cell disorders
- Transplant-related hematology
Therapeutic interest extends to CAR T-cell therapy, allogeneic transplantation, and treatment strategies for minimal residual disease and refractory hematologic disease.
Cardiovascular medicine
Clinical research includes acute coronary syndrome, myocardial infarction, heart failure, atrial fibrillation, atherosclerotic cardiovascular disease, and hypertension, with attention to both prevention and management of recurrent events.
- Ischemic heart disease
- Heart failure syndromes
- Thromboembolic prevention
- Cardiometabolic risk
- Lipid disorders
Additional work covers transthyretin amyloid cardiomyopathy, pulmonary hypertension, and vascular risk reduction in patients with elevated lipoprotein(a) and chronic kidney disease.
Nephrology and renal-cardiometabolic disease
As a nephrology investigator, the clinical focus includes chronic kidney disease, end-stage kidney disease, proteinuria, hypertensive kidney disease, and kidney involvement in broader cardiometabolic disease.
- Chronic kidney disease
- Renal protection
- Cardiorenal syndromes
- Diabetic kidney disease
- Electrolyte and metabolic complications
Research involvement also includes autosomal dominant polycystic kidney disease, hyperkalemia, and renal outcomes in patients with heart failure and atherosclerotic cardiovascular disease.
Immune-mediated and inflammatory disorders
The investigator also participates in trials across inflammatory bowel disease, systemic lupus erythematosus, psoriatic arthritis, polymyalgia rheumatica, primary Sjögren’s disease, and asthma, reflecting interest in immune-driven conditions.
- Crohn’s disease
- Ulcerative colitis
- Autoimmune rheumatic disease
- Severe asthma
- Chronic obstructive pulmonary disease
Additional areas include pulmonary sarcoidosis, multiple sclerosis, and immune thrombocytopenia, alongside infection-related studies in severe influenza and cytomegalovirus infection.
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