Jose Fernando R. P.
- Country
- Spain
- Department
- #4508: Cardiología
Research Overview
- Phase IIb Randomized Double‑Blind Placebo‑Controlled Study of Eplontersen Plus ALXN2220 Versus Eplontersen + Placebo in Adults with Transthyretin‑Mediated Amyloid Cardiomyopathy
- Phase IIIb Randomized Study of Inclisiran on Atherosclerotic Plaque Progression in Non-obstructive Coronary Artery Disease with Statin Therapy
- Efficacy of Esmolol Hydrochloride in Diagnosing Cardiovascular Disorders Induced by Cirrhosis, Diabetes Mellitus, and Cardiotoxic Treatments
Data & Insights
Has run more than one trial at 43 of 118 partner sites.
Specializations
Thoracic Oncology
Clinical research in non-small cell lung cancer, small cell lung cancer, and other advanced thoracic malignancies, with interest in biomarker-defined disease and treatment-resistant settings.
- Advanced non-small cell lung cancer
- Small cell lung cancer
- Head and neck squamous cell carcinoma
- Esophageal cancer
Work also extends to lung cancer subtypes with actionable molecular alterations and metastatic disease involving the chest and upper aerodigestive tract.
Breast and Gynecologic Cancer
Therapeutic involvement includes breast cancer across hormone receptor-positive, HER2-negative, HER2-positive, and triple-negative disease, together with major activity in ovarian cancer and endometrial cancer.
- Advanced breast cancer
- Triple-negative breast cancer
- Ovarian cancer
- Endometrial cancer
Research interests also cover cervical cancer, fallopian tube cancer, and gastroesophageal junction adenocarcinoma in advanced and recurrent disease.
Genitourinary and Renal Malignancies
The investigator is active in renal cell carcinoma, urothelial carcinoma, and prostate cancer, including metastatic and treatment-refractory presentations.
- Renal cell carcinoma
- Urothelial carcinoma
- Metastatic prostate cancer
- Bladder cancer
Additional focus includes upper tract urothelial carcinoma and high-risk kidney cancer populations requiring post-surgical or systemic treatment strategies.
Hematologic Malignancies
Research activity spans acute myeloid leukemia, lymphoma, multiple myeloma, and related marrow disorders, with attention to relapsed and refractory blood cancers.
- Acute myeloid leukemia
- Diffuse large B-cell lymphoma
- Chronic lymphocytic leukemia
- Myelodysplastic syndrome
Therapeutic interests also include mantle cell lymphoma, follicular lymphoma, Waldenström macroglobulinemia, and graft-versus-host disease.
Cardiometabolic and Immune-Mediated Disease
Beyond oncology, the investigator is involved in studies of atherosclerotic cardiovascular disease, heart failure, obesity, and diabetes mellitus, along with immune-mediated and inflammatory disorders.
- Atherosclerotic cardiovascular disease
- Heart failure
- Systemic lupus erythematosus
- Rheumatoid arthritis
Additional areas include asthma, myasthenia gravis, kidney disease, and amyloidosis, reflecting engagement with chronic multisystem therapeutic domains.
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