Jörn S.
- Country
- Germany
- Department
- Klinik für Innere Medizin II
Research Overview
- N1T-MC-MALO: A Master Protocol for a Randomized, Controlled, Clinical Trial of Multiple Pharmacologic Agents in Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease Who Are at Increased Risk of Developing Major Adverse Liver Outcomes (SYNERGY-Outcomes); N1T-MC-TZ01 Tirzepatide in participants with high-risk MASLD; N1T-MC-RT01 Retatrutide in participants with high-risk MASLD
- Phase 3 Randomized Double‑Blind Placebo‑Controlled Study of Efimosfermin Alfa in Adults with Biopsy‑Confirmed F2–F3 Metabolic Dysfunction‑Associated Steatohepatitis
- Phase 3 Randomized Double‑Blind Placebo‑Controlled Study of Efimosfermin Alfa Safety and Tolerability in Adults with F2‑F3 Metabolic Dysfunction‑Associated Steatohepatitis
Data & Insights
Has run more than one trial at 182 of 330 partner sites.
Specializations
Liver Disease Management
Specializes in treating various forms of non-alcoholic steatohepatitis (NASH) and metabolic dysfunction-associated steatohepatitis (MASH), with particular focus on advanced fibrosis stages and cirrhotic complications.
- Fibrosis Assessment and Treatment
- Cirrhosis Management
- Portal Hypertension
Investigates innovative therapeutic approaches for liver fibrosis regression and prevention of disease progression.
Autoimmune and Cholestatic Conditions
Focuses on treating autoimmune hepatitis and primary biliary cholangitis (PBC), particularly in cases with inadequate response to conventional therapies.
- Immune System Modulation
- Cholestasis Treatment
- Alternative Therapeutic Strategies
Evaluates novel therapeutic agents for managing chronic liver conditions resistant to standard treatments.
Hepatobiliary Oncology
Specializes in the treatment of hepatocellular carcinoma and cholangiocarcinoma, including both early-stage and advanced disease management.
- Surgical Interventions
- Targeted Therapies
- Combination Treatment Approaches
Develops therapeutic strategies for primary liver cancers and biliary tract malignancies.
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