Johannes D.
- Country
- Germany
- Department
- Medizinische Klinik und Poliklinik II
Research Overview
- Evaluation of Adverse Events, Pharmacokinetics, and Disease Activity of Oral ABBV-101 in Adult Patients with Select B-Cell Malignancies
- Phase 2 Study on Epcoritamab Monotherapy or Combined with Lenalidomide for Anthracycline-Ineligible Diffuse Large B-Cell Lymphoma Patients
- Phase 3 Randomized Study of Tafasitamab, Lenalidomide, and Rituximab in Relapsed/Refractory Follicular and Marginal Zone Lymphoma
Data & Insights
Has run more than one trial at 132 of 289 partner sites.
Specializations
Lymphoma Research
The investigator specializes in treating various forms of B-cell lymphomas, with particular focus on diffuse large B-cell lymphoma (DLBCL) and follicular lymphoma. Their research encompasses both newly diagnosed cases and relapsed/refractory disease states.
- Aggressive B-cell lymphomas
- Marginal zone lymphoma
- Non-Hodgkin lymphoma variants
Research activities include evaluation of novel therapeutic combinations for enhanced treatment outcomes in lymphoma patients.
Therapeutic Innovation
The investigator explores innovative treatment approaches using bispecific antibodies and antibody-drug conjugates. Their work includes assessment of novel agents such as epcoritamab, mosunetuzumab, and tafasitamab.
- Combination therapy strategies
- Immunotherapy applications
- Novel therapeutic agents
Focus areas include development of chemotherapy-light treatment approaches for specific patient populations.
Specialized Treatment Areas
The investigator conducts research in chronic lymphocytic leukemia and small lymphocytic lymphoma, with emphasis on treatment-resistant cases. Their work extends to investigating therapeutic options for elderly patients and those unsuitable for standard treatment regimens.
- Treatment-resistant diseases
- Age-specific therapeutic approaches
- Alternative treatment strategies
Clinical investigations include assessment of safety and efficacy in various B-cell malignancies.
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