Johan V. L.
- Country
- The Netherlands
- Department
- Paediatric Gastroenterology
Research Overview
- A Phase 3, Multi-Center Study to Evaluate the Pharmacokinetics, Efficacy, and Safety of Risankizumab with Open-Label Induction, Randomized Double-Blind Maintenance, and Long-Term Extension Periods in Pediatric Subjects (2 to < 18 Years of Age) with Moderately to Severely Active Crohn's Disease
- I6T-MC-AMBA - A Multicenter, Phase 3, Open-Label Study to Investigate the Efficacy, Pharmacokinetics, and Safety of Mirikizumab in Participants 2 Years to Less Than 18 Years of Age with Moderately to Severely Active Ulcerative Colitis
- A Phase 3 Multicenter Study to Evaluate Efficacy, Safety, and Pharmacokinetics of Upadacitinib with Open-Label Induction, Randomized, Double-Blind Maintenance and Open-Label Long-Term Extension in Pediatric Subjects with Moderately to Severely Active Ulcerative Colitis and Inadequate Response, Intolerance, or Medical Contraindications to Corticosteroids, Immunosuppressants, and/or Biologic Therapy
Data & Insights
Has run more than one trial at 16 of 64 partner sites.
Specializations
Inflammatory Bowel Disease Treatment
The investigator specializes in treating pediatric inflammatory bowel diseases, with particular focus on therapeutic approaches for children and adolescents aged 2 to 18 years.
- Ulcerative Colitis Management
- Crohn's Disease Treatment
- Pediatric Gastroenterology
Expertise includes addressing both moderate and severe manifestations of these conditions in young patients.
Novel Therapeutic Applications
Focuses on investigating innovative treatments including biological therapies and targeted interventions for pediatric gastrointestinal conditions.
- Mirikizumab Applications
- Risankizumab Treatment
- Upadacitinib Therapy
Specializes in evaluating treatment responses in cases resistant to conventional therapies.
Treatment Response Assessment
Evaluates clinical outcomes in pediatric gastroenterological conditions, particularly focusing on treatment efficacy in complex cases.
- Clinical Remission Evaluation
- Long-term Treatment Outcomes
- Therapeutic Response Monitoring
Examines treatment effectiveness in patients with inadequate response to standard therapies.
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