person

Joel U.

Country
France
Department
250006: Service Ophtalmologie

Research Overview

Data & Insights

medical_services
Primary Speciality
Main therapeutic area

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Return Partnerships
Recurring site collaborations
0
Sites with multiple studies

Has run more than one trial at 0 of 68 partner sites.

Specializations

Retinal Vascular Diseases

Therapeutic strategies targeting fluid accumulation and vascular leakage in the retina.

  • Management of diabetic macular edema with sustained‑release corticosteroid implants
  • Evaluation of anti‑VEGF agents for macular telangiectasia type 1
  • Optimization of treatment regimens for retinal edema secondary to systemic disease

Clinical activity is centered at a dedicated ophthalmology service in Rouen.

Age‑Related Macular Degeneration

Interventions aimed at slowing disease progression and preserving visual function.

  • Long‑term safety of the Port Delivery System for neovascular AMD
  • Oral complement inhibition to reduce growth of geographic atrophy
  • Assessment of novel pharmacologic agents for dry AMD

Focus includes both neovascular and atrophic disease phenotypes.

Gynecologic Oncology

Targeted and cytoreductive approaches for epithelial ovarian malignancies.

  • Use of hyperthermic intraperitoneal chemotherapy (HIPEC) in advanced ovarian cancer
  • Integration of surgical debulking strategies with systemic therapy
  • Evaluation of treatment sequencing in fallopian‑tube and peritoneal ovarian cancers

Research supports multidisciplinary care pathways.

Gastro‑intestinal and Anal Oncology

Combined modality regimens for locally advanced and metastatic gastrointestinal tumors.

  • Induction chemotherapy followed by chemoradiotherapy for anal squamous cell carcinoma
  • Combination of trifluridine/tipiracil with anti‑angiogenic agents for metastatic oesophagogastric adenocarcinoma
  • Assessment of disease‑free survival endpoints in high‑risk gastrointestinal cancers

Efforts aim to improve long‑term outcomes in aggressive disease settings.

Hormone‑Responsive Breast Cancer

Adjuvant strategies for estrogen‑receptor positive, HER2‑negative disease in older patients.

  • Comparison of chemotherapy alone versus chemotherapy plus endocrine therapy
  • Stratification by genomic grade to guide treatment intensity
  • Evaluation of overall survival benefits in the elderly population

Research integrates molecular profiling with clinical decision‑making.

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