Joanna K. G.
- Country
- Poland
- Department
- Oncologie
Research Overview
- Study of Inavolisib with Trastuzumab and Pertuzumab as Maintenance Therapy in Patients with HER2‑Positive PIK3CA‑Mutated Locally Advanced or Metastatic Breast Cancer
- Phase III Randomized Controlled Trial of Abemaciclib Plus Endocrine Therapy Versus Endocrine Therapy in HR+/HER2- Early Breast Cancer with Intermediate to High Risk
- Evaluation of Gene Expression-Driven Adjuvant Chemotherapy Versus Standard Care in Premenopausal HR-Positive/HER2-Negative Breast Cancer Using Paclitaxel and Drug Combination
Data & Insights
Has run more than one trial at 21 of 217 partner sites.
Specializations
Thoracic and Breast Oncology
The investigator is involved in clinical research across non-small cell lung cancer, small cell lung cancer, and advanced breast cancer, including hormone receptor-positive, HER2-negative, HER2-positive, and triple-negative disease. The portfolio also includes resectable, locally advanced, metastatic, and recurrence-focused solid tumor settings.
- Non-small cell lung cancer
- Small cell lung cancer
- Breast cancer
- Triple-negative breast cancer
- HER2-positive breast cancer
Research activity also extends to biomarker-defined disease groups, including EGFR-mutated, ALK-positive, KRAS G12C-mutant, and PD-L1-selected tumors, reflecting a strong focus on targeted oncology.
Hematologic Malignancies
Clinical trial involvement covers a wide range of blood cancers, with emphasis on lymphoma, leukemia, multiple myeloma, and related marrow disorders. The disease spectrum includes aggressive, relapsed, refractory, and newly diagnosed hematologic conditions.
- Diffuse large B-cell lymphoma
- Classical Hodgkin lymphoma
- Acute myeloid leukemia
- Multiple myeloma
- Myelodysplastic syndrome
The investigator is also engaged in studies involving CAR T-cell therapy, bispecific antibodies, and other advanced immuno-oncology approaches for B-cell malignancies and T-cell lymphomas.
Melanoma and Solid Tumor Immunotherapy
Research interests include advanced and resected melanoma, head and neck squamous cell carcinoma, gastric cancer, colorectal cancer, and other difficult-to-treat solid tumors. The portfolio spans both metastatic disease and adjuvant settings.
- Melanoma
- Head and neck squamous cell carcinoma
- Gastric cancer
- Colorectal cancer
- Solid tumors
Trial activity includes immune checkpoint-based strategies and other novel antitumor therapies aimed at improving outcomes in advanced and recurrent malignancies.
Cardiovascular and Metabolic Disease
The investigator is also active in studies of atherosclerotic cardiovascular disease, myocardial infarction, heart failure, atrial fibrillation, and hypertension. This includes work in both prevention and treatment-oriented cardiovascular settings.
- Atherosclerotic cardiovascular disease
- Heart failure
- Atrial fibrillation
- Myocardial infarction
- Hypertension
Metabolic research interests include hyperlipidemia, obesity, type 2 diabetes, and hypertriglyceridemia, with attention to cardiometabolic risk reduction.
Autoimmune, Neurologic, and Rare Disease Areas
The clinical portfolio includes myasthenia gravis, multiple sclerosis, systemic lupus erythematosus, rheumatoid arthritis, and interstitial lung disease. Additional interests extend to rare immune-mediated and neurologic disorders.
- Myasthenia gravis
- Multiple sclerosis
- Systemic lupus erythematosus
- Rheumatoid arthritis
- Interstitial lung disease
Research involvement also includes amyloidosis, myelofibrosis, mastocytosis, hemophilia, and selected pediatric and hereditary conditions, broadening the therapeutic scope beyond oncology.
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