Joan C. F.
- Country
- Spain
- Department
- Rheumatology Dept
Research Overview
- Evaluation of GSK4527363 in Systemic Lupus Erythematosus and Healthy Participants, Including Chinese and Japanese Cohorts
- Evaluation of Budoprutug (TNT119) Efficacy and Safety in Patients with Systemic Lupus Erythematosus
- Evaluation of Frexalimab (SAR441344) Efficacy and Safety in Active Systemic Lupus Erythematosus: A Randomized, Double-Blind, Placebo-Controlled Phase 2 Study
Data & Insights
Has run more than one trial at 129 of 243 partner sites.
Specializations
Inflammatory Rheumatic Diseases
Clinical research activity is concentrated in rheumatology, with involvement in immune-mediated joint and connective tissue disorders that include rheumatoid arthritis, psoriatic arthritis, and axial spondyloarthritis. The portfolio also extends to systemic inflammatory conditions such as systemic lupus erythematosus, systemic sclerosis, Sjögren’s syndrome, and polymyalgia rheumatica.
- Rheumatoid arthritis
- Psoriatic arthritis
- Axial spondyloarthritis
- Systemic lupus erythematosus
- Sjögren’s syndrome
Additional interests include giant cell arteritis, diffuse cutaneous systemic sclerosis, and polymyositis or dermatomyositis, reflecting a strong focus on chronic autoimmune disease management.
Gastrointestinal and Hepatic Disorders
The investigator is involved in clinical studies across inflammatory bowel disease and hepatobiliary medicine, with work spanning Crohn’s disease, ulcerative colitis, and primary biliary cholangitis. Research also covers advanced liver conditions such as compensated cirrhosis, hepatic encephalopathy, and metabolic dysfunction-associated steatohepatitis.
- Crohn’s disease
- Ulcerative colitis
- Primary biliary cholangitis
- Compensated cirrhosis
- Metabolic dysfunction-associated steatohepatitis
Other areas include acute pancreatitis, chronic liver disease, and cholestatic pruritus, indicating a broad therapeutic interest in digestive and hepatobiliary complications.
Oncology and Genitourinary Malignancies
Substantial activity is present in oncology, particularly breast cancer, prostate cancer, bladder cancer, and non-small cell lung cancer. The investigator is also engaged in studies of colorectal cancer, renal cell carcinoma, and urothelial carcinoma, covering both localized and advanced disease settings.
- Breast cancer
- Prostate cancer
- Bladder cancer
- Non-small cell lung cancer
- Urothelial carcinoma
Additional interests include triple-negative breast cancer, metastatic colorectal cancer, renal cell carcinoma, and melanoma, showing involvement in solid-tumor therapeutics with a strong genitourinary emphasis.
Respiratory and Infectious Diseases
Clinical research also includes asthma, severe community-acquired pneumonia, acute respiratory distress syndrome, and other respiratory tract disorders. The investigator’s infectious disease interests extend to sepsis, bacteremia, and human immunodeficiency virus infection.
- Asthma
- Severe community-acquired pneumonia
- Acute respiratory distress syndrome
- Sepsis
- Human immunodeficiency virus infection
Work in this area also touches on interstitial lung disease and chronic rhinosinusitis with nasal polyps, linking airway inflammation with broader pulmonary care.
Metabolic, Cardiovascular, and Neurologic Conditions
The remaining research landscape includes cardiovascular disease, atrial fibrillation, venous thromboembolism, and atherosclerotic cardiovascular disease, alongside metabolic disorders such as type 2 diabetes, heterozygous familial hypercholesterolemia, and severe hypertriglyceridemia. Neurologic and psychiatric interests include major depressive disorder, schizophrenia, migraine, and attention-deficit/hyperactivity disorder.
- Atrial fibrillation
- Venous thromboembolism
- Type 2 diabetes
- Major depressive disorder
- Schizophrenia
Additional activity includes prader-willi syndrome, fragile X syndrome, and chronic inflammatory demyelinating polyneuropathy, reflecting engagement with complex multisystem and neuropsychiatric therapeutic areas.
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