Jesús R. R.
- Country
- Spain
- Department
- Urology
Research Overview
- Phase 3 Randomized Trial of Intravesical Erdafitinib Delivery System vs. Single-Agent Chemotherapy in FGFR+ Intermediate-Risk Non-Muscle Invasive Bladder Cancer
- Evaluation of Progression-Free Survival in High-Risk Non-Muscle Invasive Bladder Cancer Treated with Mycobacterium bovis Bacillus Calmette-Guérin, Strain Moreau RJ
- Evaluation of Efficacy and Safety of Electromotive Mitomycin C Versus Bacillus Calmette-Guérin in High-Grade Non-Muscle Invasive Bladder Cancer
Data & Insights
Has run more than one trial at 23 of 116 partner sites.
Specializations
Bladder Cancer and Urothelial Carcinoma
The investigator concentrates on high‑risk non‑muscle invasive bladder cancer and related therapeutic strategies.
- Evaluation of intravesical therapies
- Assessment of FGFR‑targeted agents in bladder tumors
- Combination immunotherapy approaches
- Biomarker‑driven patient selection
Research aims to improve event‑free survival and reduce recurrence rates.
Prostate Cancer
Focus is placed on high‑risk localized and metastatic prostate cancer across surgical and systemic modalities.
- Adjuvant androgen deprivation therapy
- Integration of novel androgen receptor inhibitors
- Evaluation of postoperative pathological complete response
- Risk stratification using molecular profiling
Efforts target prolongation of metastasis‑free survival and overall disease control.
Renal and Kidney Disease
Work includes investigation of chronic kidney disease and renal transplant outcomes.
- Management of delayed graft function after transplantation
- Prevention of progression in end‑stage renal disease
- Therapeutic approaches for chronic venous insufficiency affecting renal hemodynamics
- Optimization of fluid resuscitation in acute kidney injury
Goal is to enhance graft longevity and preserve renal function.
Cardiovascular and Metabolic Disorders
The investigator also addresses dilated cardiomyopathy in genetic carriers and related metabolic conditions.
- Early intervention with cardioprotective agents
- Study of hypertriglyceridemia management strategies
- Evaluation of low‑dose colchicine for secondary vascular event prevention
- Assessment of blood pressure modulation in asymptomatic carriers
Therapeutic research seeks to reduce cardiac remodeling and cardiovascular risk.
Neurological and Autoimmune Diseases
Additional interest lies in multiple sclerosis and related immune‑mediated disorders.
- Comparison of high‑dose versus standard ocrelizumab
- Investigation of remibrutinib efficacy in relapsing disease
- Long‑term safety of ofatumumab in relapsing forms
- Biomarker analysis for disease progression
Studies aim to limit relapse frequency and disability accumulation.
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