Jesus P. P.
- Country
- Spain
- Department
- 6304: Neurología
Research Overview
- Safety and Tolerability of RG6496 in Huntington’s Disease Gene Expansion Carriers with the Selected Genetic Variant (POINT‑HD)
- Randomized, Double‑Blind, Placebo‑Controlled Phase 3 Trial of Oral Votoplam in Adults with Huntington’s Disease Assessing cUHDRS Progression
- Phase 2/3 Randomized, Double‑Blind, Placebo‑Controlled, Dose‑Ranging Study of SKY‑0515 in Adults with Huntington’s Disease
Data & Insights
Has run more than one trial at 16 of 86 partner sites.
Specializations
Neurodegenerative Disorders
Investigator concentrates on progressive brain diseases marked by neuronal loss and abnormal protein accumulation.
- Alzheimer Disease
- Parkinson Disease
- Amyotrophic Lateral Sclerosis
- Huntington's Disease
- Frontotemporal Dementia
- Progressive Supranuclear Palsy
Efforts aim to clarify pathogenic pathways and identify disease‑modifying interventions.
Autoimmune Neurological Conditions
Research targets immune‑mediated disorders that affect the peripheral and central nervous systems.
- Multiple Sclerosis
- Chronic Inflammatory Demyelinating Polyneuropathy
- Myasthenia Gravis
- Systemic Lupus Erythematosus
- Autoimmune Encephalitis
Studies explore immune dysregulation, biomarkers, and therapeutic modulation of pathogenic antibodies.
Neurovascular and Cerebrovascular Diseases
Investigator is engaged in conditions arising from vascular impairment of the brain.
- Acute Ischemic Stroke
- Cerebral Embolism
- Subarachnoid Hemorrhage
- CADASIL
- Transient Ischemic Attack
Work focuses on acute management, secondary prevention, and neuroprotective strategies.
Neurocognitive and Psychiatric Disorders
Clinical interest includes disorders that affect cognition, mood, and behavior.
- Major Depressive Disorder
- Schizophrenia
- Borderline Personality Disorder
- Neurocognitive Impairment
- Alzheimer's Disease Dementia
Research seeks to delineate neurobiological substrates and evaluate novel therapeutic approaches.
Neurodevelopmental and Genetic Neurological Disorders
Investigator studies early‑onset epileptic and genetic conditions affecting brain development.
- Dravet Syndrome
- Lennox‑Gastaut Syndrome
- Developmental and Epileptic Encephalopathies
- Down Syndrome
- Focal Epilepsy
Efforts aim to uncover genetic mechanisms and test precision‑medicine interventions.
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