Jesús F. F.
- Country
- Spain
- Department
- Servicio de Neumología
Research Overview
- Long-term safety and efficacy of subcutaneous lunsekimig in adults with asthma: An open-label extension study
- Phase 2b/3 Randomized Double‑Blind Placebo‑Controlled Study Evaluating Efficacy and Safety of Lunsekimig in Adults with Inadequately Controlled Eosinophilic COPD
- Phase 3b/4 Randomized Double‑Blind Study of Depemokimab 100 mg SC Q26 weeks vs Placebo on Exacerbations and Lung‑Function Decline in Adults/Adolescents with Type 2 Asthma
Data & Insights
Has run more than one trial at 84 of 224 partner sites.
Specializations
Cardiometabolic and lipid disorders
Clinical research activity includes atherosclerotic cardiovascular disease, high cardiovascular risk, hypertension, dyslipidemia, elevated lipoprotein(a), severe hypertriglyceridemia, and obesity or overweight, with attention to prevention of major cardiovascular events and related risk reduction.
- Cardiovascular outcomes
- Lipid management
- Weight-related metabolic disease
- Blood pressure control
The therapeutic focus also extends to cardiovascular safety and long-term management of metabolic conditions linked to vascular disease.
Dermatology and immune-mediated skin disease
Work in acne vulgaris, atopic dermatitis, chronic spontaneous urticaria, prurigo nodularis, plaque psoriasis, and cutaneous lupus erythematosus reflects a strong interest in inflammatory skin disorders and symptom control.
- Inflammatory dermatoses
- Itch and skin barrier disease
- Autoimmune cutaneous disease
- Psoriatic skin disease
Research also includes long-term safety and treatment durability in chronic dermatologic conditions.
Rheumatology and systemic autoimmune disease
Clinical involvement spans systemic lupus erythematosus, rheumatoid arthritis, psoriatic arthritis, axial spondyloarthritis, primary Sjögren’s disease, and other rheumatologic disease with systemic inflammatory activity.
- Autoimmune arthritis
- Systemic connective tissue disease
- Inflammatory joint disease
- Multisystem immune dysregulation
Therapeutic interests include disease activity reduction, symptom relief, and sustained control of chronic immune-mediated disorders.
Respiratory and upper airway disease
Research activity covers asthma, bronchiectasis, and chronic rhinosinusitis with nasal polyps, with additional attention to airway inflammation and respiratory symptom burden.
- Asthma control
- Chronic airway inflammation
- Nasal polyposis
- Bronchiectatic disease
These studies align with therapeutic development in both lower and upper airway inflammatory disease.
Neurology, gastroenterology, oncology, and supportive care
Additional trial involvement includes migraine, Rett syndrome, coeliac disease, Crohn’s disease, cancer-associated cachexia, non-small cell lung cancer, and melanoma, alongside influenza immunisation and management of treatment-related symptoms such as nausea and vomiting.
- Headache and migraine prevention
- Inflammatory bowel disease
- Oncology and cachexia
- Vaccine research
The portfolio also includes vitamin D deficiency and other supportive care areas relevant to chronic disease management.
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