Jesús F. A.
- Country
- Spain
- Department
- Infectious Diseases Department
Research Overview
- Phase III Randomized Study of Olorofim Versus Liposomal Amphotericin B in Patients with Invasive Aspergillosis
- Phase 3 Randomized Study of Echinocandin Followed by Ibrexafungerp vs. Echinocandin Followed by Fluconazole in Invasive Candidiasis/Candidemia
- Efficacy and Safety Evaluation of Amikacin Liposome Inhalation Suspension with Azithromycin and Ethambutol in Adult Patients with MAC-Induced NTM Lung Infection
Data & Insights
Has run more than one trial at 55 of 127 partner sites.
Specializations
Infectious Diseases and Antimicrobial Therapy
Clinical activity includes nontuberculous mycobacterial lung infection, tuberculosis, candidemia, invasive fungal infection, bacteremia, and viral infection management, with attention to complex and treatment-resistant infectious syndromes.
- HIV infection
- Chronic hepatitis D
- Clostridioides difficile infection
- Septic shock
The portfolio also extends to post-transplant infection, bronchiectasis with chronic Pseudomonas aeruginosa infection, and other difficult-to-treat infectious diseases.
Oncology and Hematologic Malignancies
Research spans a broad range of solid tumors and blood cancers, including breast cancer, non-small cell lung cancer, urothelial carcinoma, ovarian cancer, renal cell carcinoma, and prostate cancer.
- Acute myeloid leukemia
- Multiple myeloma
- Diffuse large B-cell lymphoma
- Chronic lymphocytic leukemia
Additional interest is evident in melanoma, head and neck squamous cell carcinoma, gastrointestinal cancers, and neuroendocrine tumors.
Cardiovascular and Metabolic Disorders
Investigational work covers atherosclerotic cardiovascular disease, acute coronary syndrome, myocardial infarction, heart failure, and stroke prevention, alongside metabolic risk conditions.
- Hypercholesterolemia
- Obesity
- Type 2 diabetes mellitus
- Heterozygous familial hypercholesterolemia
Therapeutic focus also includes pulmonary embolism, atrial fibrillation, and calcific aortic valve stenosis.
Autoimmune, Inflammatory, and Neurologic Diseases
Clinical interests include systemic lupus erythematosus, rheumatoid arthritis, Sjögren’s disease, Behçet’s disease, and juvenile idiopathic arthritis, reflecting engagement with immune-mediated disease.
- Multiple sclerosis
- Myasthenia gravis
- Thyroid eye disease
- Bullous pemphigoid
Research activity also includes idiopathic inflammatory myopathy, psoriasis, vitiligo, and Parkinson’s disease.
Hepatology, Renal Disease, and Transplant-Related Conditions
Work in this area includes cirrhosis, acute-on-chronic liver failure, hepatocellular carcinoma, hepatic encephalopathy, and non-alcoholic steatohepatitis, with a strong focus on advanced liver disease.
- Chronic kidney disease
- IgA nephropathy
- Amyloidosis
- Graft-versus-host disease
Additional therapeutic interest includes renal cell carcinoma, portal hypertension, chronic liver disease, and post-transplant complications.
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