Jelle D.
- Country
- Belgium
- Department
- Neurology
Research Overview
- Colchicine for Reducing Dependency and MACE in Acute Intracerebral Hemorrhage Survivors with Atherosclerotic Risk: Randomized Placebo-Controlled Trial
- Evaluation of Edoxaban Versus Nonanticoagulant Therapy in High-Risk Atrial Fibrillation Patients with Prior Intracranial Hemorrhage
- A Phase 3, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Study to Demonstrate the Efficacy and Safety of Milvexian, an Oral Factor XIa Inhibitor, for Stroke Prevention after an Acute Ischemic Stroke or High-Risk Transient Ischemic Attack
Data & Insights
Has run more than one trial at 13 of 270 partner sites.
Specializations
Neurodegenerative Disorders
Investigation of progressive brain diseases such as Alzheimer's disease and Parkinson's disease that lead to cognitive decline and motor impairment.
- Alzheimer's disease
- Parkinson's disease
- Amyotrophic Lateral Sclerosis
- Frontotemporal dementia
Clinical studies assess disease‑modifying and symptomatic agents for these conditions.
Neuroinflammatory & Autoimmune Neurology
Focus on immune‑mediated disorders of the nervous system, including multiple sclerosis, myasthenia gravis, and systemic lupus erythematosus with neuropsychiatric involvement.
- Multiple sclerosis
- Myasthenia gravis
- Neuropsychiatric systemic lupus erythematosus
- Chronic inflammatory demyelinating polyneuropathy
Trials evaluate targeted immunotherapies and biologics for disease control.
Neurogenetic & Neuromuscular Disorders
Research on inherited neuromuscular diseases such as spinal muscular atrophy, Pompe disease, and mitochondrial myopathies.
- Spinal muscular atrophy
- Pompe disease
- Mitochondrial myopathy
- Duchenne muscular dystrophy
Studies address gene‑based and enzyme‑replacement strategies.
Cerebrovascular & Stroke
Clinical focus on acute and secondary prevention of cerebrovascular events, including ischemic stroke and transient ischemic attack.
- Acute ischemic stroke
- Transient ischemic attack
- Intracerebral hemorrhage
- Post‑stroke cognitive impairment
Investigations test antithrombotic, neuroprotective, and rehabilitation interventions.
Neuro‑Oncology & Brain Tumors
Study of primary central nervous system neoplasms such as glioblastoma and metastatic brain lesions.
- Glioblastoma
- Brain metastasis
- Low‑grade astrocytoma
- Primary CNS lymphoma
Clinical trials explore targeted agents, immunotherapies, and novel delivery methods.
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